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Analysis of Medication Adherence and Its Influencing Factors in Patients with Schizophrenia in the Chinese Institutional Environment

Author

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  • Wei Yu

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China
    These authors contributed equally to this work.)

  • Jie Tong

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China
    These authors contributed equally to this work.)

  • Xirong Sun

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Fazhan Chen

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Jie Zhang

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Yu Pei

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Tingting Zhang

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Jiechun Zhang

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

  • Binggen Zhu

    (Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, 165 Sanlin Road, Shanghai 200124, China)

Abstract

Background: Factors related to medication adherence in patients with schizophrenia have always been key to the treatment and rehabilitation of these patients. However, the treatment modes in different countries are not the same, and there is no research on the factors influencing medication adherence under different mental health service modes. Objectives: The purpose of this study was to explore medication adherence and its influencing factors in patients with schizophrenia in the Chinese institutional environment. Methods: We conducted a cross-sectional study of hospitalized persons living with schizophrenia from November 2018 to January 2019. A systematic sampling method was used to select 217 hospitalized persons living with schizophrenia. The Medication Adherence Rating Scale (MARS), Positive and Negative Syndrome Scale (PANSS), General Self-Efficacy Scale (GSES), Schizophrenia Quality of Life Scale (SQLS), and Scale of Social Skills for Psychiatric Inpatients (SSPI) were used to explore medication compliance and its influencing factors in the Chinese institutional environment. Results: The descriptive analysis and ANOVA showed that there were no significant differences in medication adherence when assessed by demographic characteristics such as sex, marital status, and education level ( p > 0.05). A correlation analysis showed that there was no significant correlation between medication adherence and mental symptoms ( p > 0.05) but that there was a positive correlation with self-efficacy, quality of life, and activities of daily living ( p < 0.01). The linear regression analysis showed that self-efficacy, psychosocial factors, symptoms/side effects, and activities of daily living had significant effects on medication adherence (F = 30.210, p < 0.001). Conclusions: Our findings show that the self-efficacy, quality of life, and social function of patients with schizophrenia are important self-factors influencing medication adherence in the Chinese institutional environment.

Suggested Citation

  • Wei Yu & Jie Tong & Xirong Sun & Fazhan Chen & Jie Zhang & Yu Pei & Tingting Zhang & Jiechun Zhang & Binggen Zhu, 2021. "Analysis of Medication Adherence and Its Influencing Factors in Patients with Schizophrenia in the Chinese Institutional Environment," IJERPH, MDPI, vol. 18(9), pages 1-10, April.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:9:p:4746-:d:546073
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    References listed on IDEAS

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    1. Jim van Os & Gunter Kenis & Bart P. F. Rutten, 2010. "The environment and schizophrenia," Nature, Nature, vol. 468(7321), pages 203-212, November.
    2. Shan Lu & Yajie Zhao & Jianjiao Liu & Feng Xu & Zhiwen Wang, 2021. "Effectiveness of Horticultural Therapy in People with Schizophrenia: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(3), pages 1-16, January.
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    Cited by:

    1. Wenwen Cao & Chenglin Cao & Xin Zheng & Kai Ji & Qiming Liang & Yunwei Wu & Zhi Hu & Zhongliang Bai, 2022. "Factors Associated with Medication Adherence among Community-Dwelling Older People with Frailty and Pre-Frailty in China," IJERPH, MDPI, vol. 19(23), pages 1-10, November.

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