IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i7p3742-d529550.html
   My bibliography  Save this article

Do Rural Second Homes Shape Commensal Microbiota of Urban Dwellers? A Pilot Study among Urban Elderly in Finland

Author

Listed:
  • Mika Saarenpää

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland)

  • Marja I. Roslund

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland)

  • Riikka Puhakka

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland)

  • Mira Grönroos

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland)

  • Anirudra Parajuli

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
    Department of Medicine, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden)

  • Nan Hui

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
    School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan RD. Minhang District, Shanghai 200240, China)

  • Noora Nurminen

    (Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland)

  • Olli H. Laitinen

    (Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland)

  • Heikki Hyöty

    (Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland)

  • Ondrej Cinek

    (Second Faculty of Medicine, Charles University, V Úvalu 84, 150 06 Prague 5, Czech Republic)

  • Aki Sinkkonen

    (Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
    Natural Resources Institute Finland, Itäinen Pitkäkatu 4 A, 20520 Turku, Finland)

  • the ADELE Research Group

    (The ADELE research group: Damiano Cerrone, Mira Grönroos, Nan Hui, Heikki Hyöty, Olli H. Laitinen, Iida Mäkelä, Noora Nurminen, Sami Oikarinen, Anirudra Parajuli, Riikka Puhakka, Juho Rajaniemi, Marja I. Roslund, Mika Saarenpää, Aki Sinkkonen, Laura Soininen, Yan Sun, Raisa Valve, Heli K. Vari.)

Abstract

According to the hygiene and biodiversity hypotheses, increased hygiene levels and reduced contact with biodiversity can partially explain the high prevalence of immune-mediated diseases in developed countries. A disturbed commensal microbiota, especially in the gut, has been linked to multiple immune-mediated diseases. Previous studies imply that gut microbiota composition is associated with the everyday living environment and can be modified by increasing direct physical exposure to biodiverse materials. In this pilot study, the effects of rural-second-home tourism were investigated on the gut microbiota for the first time. Rural-second-home tourism, a popular form of outdoor recreation in Northern Europe, North America, and Russia, has the potential to alter the human microbiota by increasing exposure to nature and environmental microbes. The hypotheses were that the use of rural second homes is associated with differences in the gut microbiota and that the microbiota related to health benefits are more diverse or common among the rural-second-home users. Based on 16S rRNA Illumina MiSeq sequencing of stool samples from 10 urban elderly having access and 15 lacking access to a rural second home, the first hypothesis was supported: the use of rural second homes was found to be associated with lower gut microbiota diversity and RIG-I-like receptor signaling pathway levels. The second hypothesis was not supported: health-related microbiota were not more diverse or common among the second-home users. The current study encourages further research on the possible health outcomes or causes of the observed microbiological differences. Activities and diet during second-home visits, standard of equipment, surrounding environment, and length of the visits are all postulated to play a role in determining the effects of rural-second-home tourism on the gut microbiota.

Suggested Citation

  • Mika Saarenpää & Marja I. Roslund & Riikka Puhakka & Mira Grönroos & Anirudra Parajuli & Nan Hui & Noora Nurminen & Olli H. Laitinen & Heikki Hyöty & Ondrej Cinek & Aki Sinkkonen & the ADELE Research , 2021. "Do Rural Second Homes Shape Commensal Microbiota of Urban Dwellers? A Pilot Study among Urban Elderly in Finland," IJERPH, MDPI, vol. 18(7), pages 1-19, April.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:7:p:3742-:d:529550
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/7/3742/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/7/3742/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Lawrence A. David & Corinne F. Maurice & Rachel N. Carmody & David B. Gootenberg & Julie E. Button & Benjamin E. Wolfe & Alisha V. Ling & A. Sloan Devlin & Yug Varma & Michael A. Fischbach & Sudha B. , 2014. "Diet rapidly and reproducibly alters the human gut microbiome," Nature, Nature, vol. 505(7484), pages 559-563, January.
    2. Kati Pitkänen & Jenni Lehtimäki & Riikka Puhakka, 2020. "How do Rural Second Homes Affect Human Health and Well-being? Review of Potential Impacts," IJERPH, MDPI, vol. 17(18), pages 1-16, September.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Jing Zhao & Yukari Nagai & Wei Gao & Tao Shen & Youming Fan, 2023. "The Effects of Interior Materials on the Restorativeness of Home Environments," IJERPH, MDPI, vol. 20(14), pages 1-11, July.
    2. Joe J. Lim & Christian Diener & James Wilson & Jacob J. Valenzuela & Nitin S. Baliga & Sean M. Gibbons, 2023. "Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    3. Kenneth A. Wilson & Sudipta Bar & Eric B. Dammer & Enrique M. Carrera & Brian A. Hodge & Tyler A. U. Hilsabeck & Joanna Bons & George W. Brownridge & Jennifer N. Beck & Jacob Rose & Melia Granath-Pane, 2024. "OXR1 maintains the retromer to delay brain aging under dietary restriction," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    4. Sandra M. Holmberg & Rachel H. Feeney & Vishnu Prasoodanan P.K. & Fabiola Puértolas-Balint & Dhirendra K. Singh & Supapit Wongkuna & Lotte Zandbergen & Hans Hauner & Beate Brandl & Anni I. Nieminen & , 2024. "The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    5. Iris Chen & Yogeshwar D Kelkar & Yu Gu & Jie Zhou & Xing Qiu & Hulin Wu, 2017. "High-dimensional linear state space models for dynamic microbial interaction networks," PLOS ONE, Public Library of Science, vol. 12(11), pages 1-20, November.
    6. Joanna F Dipnall & Julie A Pasco & Michael Berk & Lana J Williams & Seetal Dodd & Felice N Jacka & Denny Meyer, 2016. "Into the Bowels of Depression: Unravelling Medical Symptoms Associated with Depression by Applying Machine-Learning Techniques to a Community Based Population Sample," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-19, December.
    7. Vinod Nikhra, 2019. "Therapeutic Potential of Gut Microbiome Manipulation: Concepts in Fecal Microbiota Transplantation," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 11(1), pages 1-9, June.
    8. Huimin Ye & Sabrina Borusak & Claudia Eberl & Julia Krasenbrink & Anna S. Weiss & Song-Can Chen & Buck T. Hanson & Bela Hausmann & Craig W. Herbold & Manuel Pristner & Benjamin Zwirzitz & Benedikt War, 2023. "Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    9. Amanda H Pendegraft & Boyi Guo & Nengjun Yi, 2019. "Bayesian hierarchical negative binomial models for multivariable analyses with applications to human microbiome count data," PLOS ONE, Public Library of Science, vol. 14(8), pages 1-23, August.
    10. Robin D Couch & Allyson Dailey & Fatima Zaidi & Karl Navarro & Christopher B Forsyth & Ece Mutlu & Phillip A Engen & Ali Keshavarzian, 2015. "Alcohol Induced Alterations to the Human Fecal VOC Metabolome," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-24, March.
    11. Mengyuan Qiu & Ji Sha & Noel Scott, 2021. "Restoration of Visitors through Nature-Based Tourism: A Systematic Review, Conceptual Framework, and Future Research Directions," IJERPH, MDPI, vol. 18(5), pages 1-18, February.
    12. Alice Risely & Kerstin Wilhelm & Tim Clutton-Brock & Marta B. Manser & Simone Sommer, 2021. "Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
    13. Narongrit Sritana & Atitaya Phungpinij, 2024. "Analysis of Oral Microbiota in Elderly Thai Patients with Alzheimer’s Disease and Mild Cognitive Impairment," IJERPH, MDPI, vol. 21(9), pages 1-15, September.
    14. Yaqing Gao & Xiaoyi Mi & Yinping Wang & Siyu Zou & Hong Zhou, 2021. "Association between Household Crowding and Violent Discipline and Neglect of Children: Analysis of Multiple Indicator Cluster Surveys in 26 Low- and Middle-Income Countries," IJERPH, MDPI, vol. 18(4), pages 1-13, February.
    15. Hania M. Taha & Alexander N. Slade & Betty Schwartz & Anna E. Arthur, 2022. "A Case–Control Study Examining the Association of Fiber, Fruit, and Vegetable Intake and the Risk of Colorectal Cancer in a Palestinian Population," IJERPH, MDPI, vol. 19(12), pages 1-11, June.
    16. Sarah L Hagerty & Kent E Hutchison & Christopher A Lowry & Angela D Bryan, 2020. "An empirically derived method for measuring human gut microbiome alpha diversity: Demonstrated utility in predicting health-related outcomes among a human clinical sample," PLOS ONE, Public Library of Science, vol. 15(3), pages 1-21, March.
    17. Patrick A. Jonge & Koen Wortelboer & Torsten P. M. Scheithauer & Bert-Jan H. Born & Aeilko H. Zwinderman & Franklin L. Nobrega & Bas E. Dutilh & Max Nieuwdorp & Hilde Herrema, 2022. "Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    18. Lharbi Dridi & Fernando Altamura & Emmanuel Gonzalez & Olivia Lui & Ryszard Kubinski & Reilly Pidgeon & Adrian Montagut & Jasmine Chong & Jianguo Xia & Corinne F. Maurice & Bastien Castagner, 2023. "Identifying glycan consumers in human gut microbiota samples using metabolic labeling coupled with fluorescence-activated cell sorting," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    19. Muntsa Rocafort & David B. Gootenberg & Jesús M. Luévano & Jeffrey M. Paer & Matthew R. Hayward & Juliet T. Bramante & Musie S. Ghebremichael & Jiawu Xu & Zoe H. Rogers & Alexander R. Munoz & Samson O, 2024. "HIV-associated gut microbial alterations are dependent on host and geographic context," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    20. Alex D Washburne & Joshua W Burby & Daniel Lacker, 2016. "Novel Covariance-Based Neutrality Test of Time-Series Data Reveals Asymmetries in Ecological and Economic Systems," PLOS Computational Biology, Public Library of Science, vol. 12(9), pages 1-14, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:7:p:3742-:d:529550. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.