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Italian Children Exposure to Bisphenol A: Biomonitoring Data from the LIFE PERSUADED Project

Author

Listed:
  • Sabrina Tait

    (Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy)

  • Fabrizia Carli

    (National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy)

  • Luca Busani

    (Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy)

  • Demetrio Ciociaro

    (National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy)

  • Veronica Della Latta

    (National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy)

  • Annalisa Deodati

    (Dipartimento Pediatrico, Universitario Ospedaliero “Bambino Gesù” Children’s Hospital, Piazza di Sant’Onofrio, 4, 00165 Rome, Italy)

  • Enrica Fabbrizi

    (Unità Operativa Complessa Pediatria e Neonatologia, Ospedale Civile Augusto Murri, Via Augusto Murri, 21, 63900 Fermo, Italy
    Civitanova Marche Hospital, ASUR MARCHE Area Vasta 3, 62012 Civitanova Marche, Italy)

  • Anna Paola Pala

    (National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy)

  • Francesca Maranghi

    (Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy)

  • Roberta Tassinari

    (Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy)

  • Giacomo Toffol

    (Associazione Culturale Pediatri, Via Montiferru, 6, 09070 Narbolia, Italy)

  • Stefano Cianfarani

    (Dipartimento Pediatrico, Universitario Ospedaliero “Bambino Gesù” Children’s Hospital, Piazza di Sant’Onofrio, 4, 00165 Rome, Italy
    Department of Systems Medicine, University of Rome Tor Vergata, Via Cracovia, 50, 00133 Rome, Italy
    Department of Women’s and Children’s Health, Karolinska Institutet and University Hospital, Solnavägen 1, 171 77 Stockholm, Sweden)

  • Amalia Gastaldelli

    (National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy)

  • Cinzia La Rocca

    (Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy)

  • LIFE PERSUADED Project Group

    (Membership of the LIFE PERSUADED Project Group is provided in the Acknowledgments.)

Abstract

A human biomonitoring (HBM) study on bisphenol A (BPA) in Italian children and adolescents was performed within the LIFE PERSUADED project, considering the residing areas, sex and age. The median urinary BPA level was 7.02 µg/L, with children living in the South of Italy or in urban areas having higher levels than those residing in the North or in rural areas. Children aged 4–6 years had higher BPA levels than those aged 7–10 and 11–14 years, but no differences were detected between sexes. The exposure in Italian children was higher compared to children from other countries, but lower than the HBM guidance value (135 µg/L). The estimated daily intake was 0.17 μg/kg body weight (bw) per day, about 24-fold below the temporary Tolerable Daily Intake of 4 μg/kg bw per day established by the European Food Safety Authority. However, this threshold was exceeded in 1.44% of the enrolled children, raising concern about the overall exposure of Italian young population.

Suggested Citation

  • Sabrina Tait & Fabrizia Carli & Luca Busani & Demetrio Ciociaro & Veronica Della Latta & Annalisa Deodati & Enrica Fabbrizi & Anna Paola Pala & Francesca Maranghi & Roberta Tassinari & Giacomo Toffol , 2021. "Italian Children Exposure to Bisphenol A: Biomonitoring Data from the LIFE PERSUADED Project," IJERPH, MDPI, vol. 18(22), pages 1-15, November.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:22:p:11846-:d:677235
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    References listed on IDEAS

    as
    1. Francesca Gorini & Elisa Bustaffa & Alessio Coi & Giorgio Iervasi & Fabrizio Bianchi, 2020. "Bisphenols as Environmental Triggers of Thyroid Dysfunction: Clues and Evidence," IJERPH, MDPI, vol. 17(8), pages 1-46, April.
    2. Ka Young Kim & Eunil Lee & Yanghee Kim, 2019. "The Association between Bisphenol A Exposure and Obesity in Children—A Systematic Review with Meta-Analysis," IJERPH, MDPI, vol. 16(14), pages 1-9, July.
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