IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i9p3085-d351766.html
   My bibliography  Save this article

Changes of Somatosensory Phenotype in the Course of Disease in Osteoarthritis Patients

Author

Listed:
  • Johanna Höper

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany
    Equally contributed.)

  • Lara Schraml

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany
    Equally contributed.)

  • Janne Gierthmühlen

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Stephanie M. Helfert

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Stefanie Rehm

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Susanne Härtig

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Ove Schröder

    (Department of Orthopedics and Trauma Surgery, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Michael Lankes

    (Private Practice for Orthopedics and Trauma Surgery am Arndtplatz, 24116 Kiel, Germany)

  • Frieder C. Traulsen

    (Private Practice for Orthopedics and Trauma Surgery am Arndtplatz, 24116 Kiel, Germany)

  • Andreas Seekamp

    (Department of Orthopedics and Trauma Surgery, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

  • Ralf Baron

    (Department of Neurology, Division of Neurological Pain Research and Therapy, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany)

Abstract

To investigate sensory changes, physical function (pF), quality of life (QoL) and pain intensity of patients with osteoarthritis (OA) in the natural course of disease, and patients undergoing total joint replacement therapy (TJR) 31 (20 females, mean age 64.6 ± 10.4 years), patients with OA were investigated with questionnaires and quantitative sensory testing (QST) in the area of referred pain at the thigh at baseline and follow-up 22–49 weeks later; changes were analyzed separately for patients with ( n = 13) and without TJR ( n = 18). In patients without TJR pain intensity, pF, QoL did not improve, and increased pain sensitivity to cold and a stronger loss of detection were observed. In patients after TJR, however, a reduction in mechanical pain sensitivity and allodynia occurred in accordance with a reduction of pain intensity and improvement of functionality while QoL did not improve. Additionally, an increased sensitivity to heat pain and a more pronounced loss of mechanical detection could be observed in this group. TJR seems to stop peripheral pain input leading to a reduction of pain intensity and central sensitization, but surgery-induced sensory changes such as peripheral sensitization and loss of detection occur. Furthermore, TJR has favorable effects on pain intensity and functionality but not QoL.

Suggested Citation

  • Johanna Höper & Lara Schraml & Janne Gierthmühlen & Stephanie M. Helfert & Stefanie Rehm & Susanne Härtig & Ove Schröder & Michael Lankes & Frieder C. Traulsen & Andreas Seekamp & Ralf Baron, 2020. "Changes of Somatosensory Phenotype in the Course of Disease in Osteoarthritis Patients," IJERPH, MDPI, vol. 17(9), pages 1-11, April.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:9:p:3085-:d:351766
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/9/3085/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/9/3085/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Bullinger, Monika, 1995. "German translation and psychometric testing of the SF-36 Health Survey: Preliminary results from the IQOLA project," Social Science & Medicine, Elsevier, vol. 41(10), pages 1359-1366, November.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Hongyun Fu & Mark VanLandingham, 2012. "Mental Health Consequences of International Migration for Vietnamese Americans and the Mediating Effects of Physical Health and Social Networks: Results From a Natural Experiment Approach," Demography, Springer;Population Association of America (PAA), vol. 49(2), pages 393-424, May.
    2. Adedokun Oluwafemi Ojelabi & Afolabi Elijah Bamgboye & Jonathan Ling, 2019. "Preference-based measure of health-related quality of life and its determinants in sickle cell disease in Nigeria," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-16, November.
    3. Marlen Rahnfeld & Johannes Wendsche & Andreas Ihle & Sandrine R. Müller & Matthias Kliegel, 2016. "Uncovering the care setting–turnover intention relationship of geriatric nurses," European Journal of Ageing, Springer, vol. 13(2), pages 159-169, June.
    4. Garbuzova, Maria & Madlener, Reinhard, 2012. "Russia’s Emerging ESCO Market: Prospects and Barriers for Energy Efficiency Investments," FCN Working Papers 6/2012, E.ON Energy Research Center, Future Energy Consumer Needs and Behavior (FCN), revised Sep 2012.
    5. Timothy Hasenoehrl & Margarete Steiner & Felix Ebenberger & Philipp Kull & Julia Sternik & Lukas Reissig & Galateja Jordakieva & Richard Crevenna, 2024. "“Back Health 24/7/365”—A Novel, Comprehensive “One Size Fits All” Workplace Health Promotion Intervention for Occupational Back Health among Hospital Employees," IJERPH, MDPI, vol. 21(6), pages 1-10, June.
    6. Myles-Jay Linton & Paul Mark Mitchell & Hareth Al-Janabi & Michael Schlander & Jeff Richardson & Angelo Iezzi & Jasper Ubels & Joanna Coast, 2020. "Comparing the German Translation of the ICECAP-A Capability Wellbeing Measure to the Original English Version: Psychometric Properties across Healthy Samples and Seven Health Condition Groups," Applied Research in Quality of Life, Springer;International Society for Quality-of-Life Studies, vol. 15(3), pages 651-673, July.
    7. van der Schee, Evelien & Braun, Bernard & Calnan, Michael & Schnee, Melanie & Groenewegen, Peter P., 2007. "Public trust in health care: A comparison of Germany, The Netherlands, and England and Wales," Health Policy, Elsevier, vol. 81(1), pages 56-67, April.
    8. Nickel, Stefan & Thiedemann, Birgit & von dem Knesebeck, Olaf, 2010. "The effects of integrated inpatient health care on patient satisfaction and health-related quality of life: Results of a survey among heart disease patients in Germany," Health Policy, Elsevier, vol. 98(2-3), pages 156-163, December.
    9. Bärbel-Maria Kurth & Ute Ellert, 2002. "The SF-36 questionnaire and its usefulness in population studies: Results of the German Health Interview and Examination Survey 1998," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 47(4), pages 266-277, July.
    10. Ulrich Wiesmann & Hans-Joachim Hannich, 2014. "A Salutogenic Analysis of the Well-Being Paradox in Older Age," Journal of Happiness Studies, Springer, vol. 15(2), pages 339-355, April.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:9:p:3085-:d:351766. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.