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Quality of Life Changes in Acute Coronary Syndromes Patients: A Systematic Review and Meta-Analysis

Author

Listed:
  • Billingsley Kaambwa

    (College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
    Joint first authors.)

  • Hailay Abrha Gesesew

    (College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
    Epidemiology, College of Health Sciences, Mekelle University, Mekelle 231, Ethiopia
    Joint first authors.)

  • Matthew Horsfall

    (College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia)

  • Derek Chew

    (College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia)

Abstract

There is little up-to-date evidence about changes in quality of life following treatment for acute coronary syndrome (ACS) patients. The main aim of this review was to assess the changes in QoL in ACS patients after treatment. We undertook a systematic review and meta-analysis of quantitative studies. The search included studies that described the change of QoL of ACS patients after receiving treatment options such as percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) and medical therapy (MT). We synthesized findings using content analysis and pooled the estimates using meta-analysis. We used the PRISMA guidelines to select and appraise the studies and report the findings. Twenty-nine (29) articles were included in the review. We found a significant improvement of QoL in ACS patients after receiving treatment. Particularly, the meta-analytic association found that the mean QoL of patients diagnosed with ACS was higher after receiving treatment compared to baseline (overall pooled mean difference = 31.88; 95% CI = 31.64–52.11, I 2 = 98) with patients on PCI having slightly lower QoL gains (pooled mean difference = 30.22; 95% CI = 29.9–30.53, I 2 = 0%) compared to those on CABG (pooled mean difference = 34.01; 95% CI = 33.66–34.37, I 2 = 0%). The review confirmed that QoL of ACS patients improved after receiving treatment therapies although varied by the treatment options and patients’ preferences. This suggests the need to perform further study on the QoL, patient preferences and physicians’ decision to prescription of treatment options.

Suggested Citation

  • Billingsley Kaambwa & Hailay Abrha Gesesew & Matthew Horsfall & Derek Chew, 2020. "Quality of Life Changes in Acute Coronary Syndromes Patients: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(18), pages 1-28, September.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:18:p:6889-:d:416634
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    References listed on IDEAS

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    1. John Brazier & Yaling Yang & Aki Tsuchiya & Donna Rowen, 2010. "A review of studies mapping (or cross walking) non-preference based measures of health to generic preference-based measures," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 11(2), pages 215-225, April.
    2. Milad Karimi & John Brazier, 2016. "Health, Health-Related Quality of Life, and Quality of Life: What is the Difference?," PharmacoEconomics, Springer, vol. 34(7), pages 645-649, July.
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    1. Luqiao Wang & Yunke Shi & Zhao Hu & Yanyan Li & Yan Ang & Pan Jing & Bangying Zhang & Xingyu Cao & Adrian Loerbroks & Jian Li & Min Zhang, 2022. "Longitudinal Associations of Work Stress with Changes in Quality of Life among Patients after Acute Coronary Syndrome: A Hospital-Based Study," IJERPH, MDPI, vol. 19(24), pages 1-12, December.

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