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Driving forces of technological change in medicine: Radical innovations induced by side effects and their impact on society and healthcare

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  • Coccia, Mario

Abstract

Technological change in medicine has complex interactions driven by demand- and supply side determinants. The epistemological position of this paper is that scientific research generates in medicine vital radical innovations (new drugs/therapies) that are associated, a posteriori, to moderate and/or severe side effects. These side effects spur feedback mechanisms, which support a co-evolution of innovation in parallel technological pathways: 1) incremental innovations with lower side effects and higher efficacy; 2) emergence of new radical innovations induced from severe side effects. Empiricist-positivist arguments support this stance and show the main role of society and healthcare in the patterns of technological innovation in medicine. Critical evidences are the foundation to state main inductive theoretical implications between observed facts.

Suggested Citation

  • Coccia, Mario, 2012. "Driving forces of technological change in medicine: Radical innovations induced by side effects and their impact on society and healthcare," Technology in Society, Elsevier, vol. 34(4), pages 271-283.
    • Handle: RePEc:eee:teinso:v:34:y:2012:i:4:p:271-283
    DOI: 10.1016/j.techsoc.2012.06.002
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    References listed on IDEAS

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    Citations

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    Cited by:

    1. Coccia, Mario, 2019. "The theory of technological parasitism for the measurement of the evolution of technology and technological forecasting," Technological Forecasting and Social Change, Elsevier, vol. 141(C), pages 289-304.
    2. Coccia M., 2014. "Technology & environment : some possible damaging effects of technological change in advanced and opulent societies," MERIT Working Papers 2014-089, United Nations University - Maastricht Economic and Social Research Institute on Innovation and Technology (MERIT).
    3. Mario Coccia, 2018. "National debts and government deficits within European Monetary Union: Statistical evidence of economic issues," Papers 1806.07830, arXiv.org.
    4. Mario Coccia, 2020. "Effects of the institutional change based on democratization on origin and diffusion of technological innovation," Papers 2001.08432, arXiv.org.
    5. Mario Coccia, 2017. "Measurement of Economic Growth, Development and Under Development: New Model and Application," Papers 1704.05015, arXiv.org.
    6. Mario Coccia & Matteo Bellitto, 2018. "Critical analysis of human progress: Its negative and positive sides in the late-capitalism," Papers 1804.09550, arXiv.org.
    7. Coccia, Mario & Wang, Lili, 2015. "Path-breaking directions of nanotechnology-based chemotherapy and molecular cancer therapy," Technological Forecasting and Social Change, Elsevier, vol. 94(C), pages 155-169.
    8. Luppicini, Rocci & So, Arthur, 2016. "A technoethical review of commercial drone use in the context of governance, ethics, and privacy," Technology in Society, Elsevier, vol. 46(C), pages 109-119.
    9. Coccia, Mario, 2017. "Asymmetric paths of public debts and of general government deficits across countries within and outside the European monetary unification and economic policy of debt dissolution," The Journal of Economic Asymmetries, Elsevier, vol. 15(C), pages 17-31.
    10. Coccia, Mario, 2016. "The relation between price setting in markets and asymmetries of systems of measurement of goods," The Journal of Economic Asymmetries, Elsevier, vol. 14(PB), pages 168-178.
    11. Mario Coccia, 2018. "The laws of the evolution of research fields," Papers 1805.03492, arXiv.org.
    12. Coccia, Mario, 2015. "The Nexus between technological performances of countries and incidence of cancers in society," Technology in Society, Elsevier, vol. 42(C), pages 61-70.
    13. Coccia, Mario, 2014. "Driving forces of technological change: The relation between population growth and technological innovation," Technological Forecasting and Social Change, Elsevier, vol. 82(C), pages 52-65.
    14. Coccia, Mario, 2015. "General sources of general purpose technologies in complex societies: Theory of global leadership-driven innovation, warfare and human development," Technology in Society, Elsevier, vol. 42(C), pages 199-226.
    15. Coccia, Mario, 2020. "Deep learning technology for improving cancer care in society: New directions in cancer imaging driven by artificial intelligence," Technology in Society, Elsevier, vol. 60(C).
    16. Klarin, Anton, 2019. "Mapping product and service innovation: A bibliometric analysis and a typology," Technological Forecasting and Social Change, Elsevier, vol. 149(C).
    17. Mario Coccia, 2018. "Socioeconomic driving forces of scientific research," Papers 1806.05028, arXiv.org.
    18. Mario Coccia, 2017. "Disruptive technologies and competitive advantage of firms in dynamic markets," IRCrES Working Paper 201704, CNR-IRCrES Research Institute on Sustainable Economic Growth - Moncalieri (TO) ITALY - former Institute for Economic Research on Firms and Growth - Torino (TO) ITALY.
    19. Coccia, Mario, 2023. "New Perspectives in Innovation Failure Analysis: A taxonomy of general errors and strategic management for reducing risks," Technology in Society, Elsevier, vol. 75(C).

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    More about this item

    Keywords

    Radical innovation; Incremental innovation; Breast cancer; Oral contraceptive pill; Side effects; Adverse effects; Medicine; Healthcare; Technological change; Drug discovery;
    All these keywords.

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General
    • O33 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Technological Change: Choices and Consequences; Diffusion Processes

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