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Hydrophilicity and hydrophobicity: Key aspects for biomedical and technological purposes

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  • Corsaro, Carmelo
  • Mallamace, Domenico
  • Neri, Giulia
  • Fazio, Enza

Abstract

In this review we discuss the role of hydrophilic/hydrophobic interplay in several processes involving water–surface interactions. For this purpose, we describe the self-organization architecture of biomacromolecules, the design of artificial biocompatible nano-devices able to deliver poorly water-soluble drugs, and the engineering of packaging materials capable to preserve food from water, dust, and microorganisms contamination. Material properties together with mutual-cooperative interactions play a crucial role to match the complexity of biological environments and desired functional products. Therefore, the comprehension and description of hydrophilic/hydrophobic interactions at molecular level represent the main steps towards the development of new biosystems with improved functionality.

Suggested Citation

  • Corsaro, Carmelo & Mallamace, Domenico & Neri, Giulia & Fazio, Enza, 2021. "Hydrophilicity and hydrophobicity: Key aspects for biomedical and technological purposes," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 580(C).
    • Handle: RePEc:eee:phsmap:v:580:y:2021:i:c:s0378437121004623
    DOI: 10.1016/j.physa.2021.126189
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    References listed on IDEAS

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    1. Festa, Giulia & Sancesario, Giulia & Corsaro, Carmelo & Longo, Sveva & Mallamace, Domenico & Fazio, Enza & Arcidiacono, Laura & Sakai, Victoria Garcia & Senesi, Roberto & Sancesario, Giuseppe & Mallam, 2019. "SANS study of Amyloid β1−40: Unfolded monomers in DMSO, multidimensional aggregates in water medium," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 517(C), pages 385-391.
    2. Corsaro, Carmelo & Maisano, Roberta & Mallamace, Domenico & Dugo, Giacomo, 2013. "1H NMR study of water/methanol solutions as a function of temperature and concentration," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(4), pages 596-601.
    3. David Chandler, 2005. "Interfaces and the driving force of hydrophobic assembly," Nature, Nature, vol. 437(7059), pages 640-647, September.
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