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Analysis of stability and Hopf bifurcation for a viral infectious model with delay

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  • Sun, Chengjun
  • Cao, Zhijie
  • Lin, Yiping

Abstract

In this paper, a four-dimensional viral infectious model with delay is considered. The stability of the two equilibria and the existence of Hopf bifurcation are investigated. It is found that there are stability switches and Hopf bifurcations occur when the delay τ passes through a sequence of critical values. Using the normal form theory and center manifold argument [Hassard B, Kazarino D, Wan Y. Theory and applications of Hopf bifurcation. Cambridge: Cambridge University Press; 1981], the explicit formulaes which determine the stability, the direction and the period of bifurcating periodic solutions are derived. Numerical simulations are carried out to illustrate the validity of the main results.

Suggested Citation

  • Sun, Chengjun & Cao, Zhijie & Lin, Yiping, 2007. "Analysis of stability and Hopf bifurcation for a viral infectious model with delay," Chaos, Solitons & Fractals, Elsevier, vol. 33(1), pages 234-245.
    • Handle: RePEc:eee:chsofr:v:33:y:2007:i:1:p:234-245
    DOI: 10.1016/j.chaos.2005.12.029
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    References listed on IDEAS

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    1. Yang, Hong-Yong & Tian, Yu-Ping, 2005. "Hopf bifurcation in REM algorithm with communication delay," Chaos, Solitons & Fractals, Elsevier, vol. 25(5), pages 1093-1105.
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    Cited by:

    1. Hu, H.Y. & Wang, Z.H., 2009. "Singular perturbation methods for nonlinear dynamic systems with time delays," Chaos, Solitons & Fractals, Elsevier, vol. 40(1), pages 13-27.
    2. Gan, Qintao & Xu, Rui & Yang, Pinghua, 2009. "Bifurcation and chaos in a ratio-dependent predator–prey system with time delay," Chaos, Solitons & Fractals, Elsevier, vol. 39(4), pages 1883-1895.
    3. Sen, Ayan & Mukherjee, Debasis, 2009. "Chaos in the delay logistic equation with discontinuous delays," Chaos, Solitons & Fractals, Elsevier, vol. 40(5), pages 2126-2132.
    4. Din, Anwarud, 2024. "Bifurcation analysis of a delayed stochastic HBV epidemic model: Cell-to-cell transmission," Chaos, Solitons & Fractals, Elsevier, vol. 181(C).

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