IDEAS home Printed from https://ideas.repec.org/a/eee/chsofr/v139y2020ics0960077920304227.html
   My bibliography  Save this article

An age-structured model for coupling within-host and between-host dynamics in environmentally-driven infectious diseases

Author

Listed:
  • Lu, Jingjing
  • Teng, Zhidong
  • Li, Yingke

Abstract

In this paper, an age-structured epidemic model for coupling within-host and between-host dynamics in environmentally-driven infectious diseases is investigated. The model is described by a mixed system of ordinary and partial differential equations which is constituted by the within-host virus infectious fast time ordinary system and the between-host disease transmission slow time age-structured system. The isolated fast system has been investigated in previous literatures, and the main results are introduced. For the isolated slow system, the basic reproduction number Rb0, the positivity and ultimate boundedness of solutions are obtained, the existence of equilibria, the local stability of equilibria, and the global stability of disease-free equilibrium are established. We see that when Rb0 ≤ 1 the system only has the disease-free equilibrium which is globally asymptotically stable, and when Rb0 > 1 the system has a unique endemic equilibrium which is local asymptotically stable. With regard to the coupled slow system, the basic reproduction number Rb, the positivity and boundedness of solutions and the existence of equilibria are firstly obtained. Particularly, the coupled slow system can exist two positive equilibria when Rb < 1 and a unique endemic equilibrium when Rb > 1. When Rb < 1 the disease-free equilibrium is local asymptotically stable, and when Rb > 1 and an additional condition is satisfied the unique endemic equilibrium is local asymptotically stable. When there exist two positive equilibria, under an additional condition the local asymptotic stability of a positive equilibrium and the instability of other positive equilibrium also are established. The numerical examples show that the additional condition may be removed. The research shows that the coupled slow age-structured system has more complex dynamical behavior than the corresponding isolated slow system.

Suggested Citation

  • Lu, Jingjing & Teng, Zhidong & Li, Yingke, 2020. "An age-structured model for coupling within-host and between-host dynamics in environmentally-driven infectious diseases," Chaos, Solitons & Fractals, Elsevier, vol. 139(C).
    • Handle: RePEc:eee:chsofr:v:139:y:2020:i:c:s0960077920304227
    DOI: 10.1016/j.chaos.2020.110024
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0960077920304227
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.chaos.2020.110024?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Cai, Yongli & Jiao, Jianjun & Gui, Zhanji & Liu, Yuting & Wang, Weiming, 2018. "Environmental variability in a stochastic epidemic model," Applied Mathematics and Computation, Elsevier, vol. 329(C), pages 210-226.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Sun, Dandan & Teng, Zhidong & Wang, Kai & Zhang, Tailei, 2023. "Stability and Hopf bifurcation in delayed age-structured SVIR epidemic model with vaccination and incubation," Chaos, Solitons & Fractals, Elsevier, vol. 168(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Liu, Qun & Jiang, Daqing & Hayat, Tasawar & Alsaedi, Ahmed & Ahmad, Bashir, 2020. "A stochastic SIRS epidemic model with logistic growth and general nonlinear incidence rate," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 551(C).
    2. de la Cruz, H. & Jimenez, J. C, 2020. "Exact pathwise simulation of multi-dimensional Ornstein–Uhlenbeck processes," Applied Mathematics and Computation, Elsevier, vol. 366(C).
    3. Selvan, T. Tamil & Kumar, M., 2023. "Dynamics of a deterministic and a stochastic epidemic model combined with two distinct transmission mechanisms and saturated incidence rate," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 619(C).
    4. Liu, Qun & Jiang, Daqing, 2020. "Stationary distribution of a stochastic cholera model with imperfect vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 550(C).
    5. Xu, Jiang & Chen, Tao & Wen, Xiangdan, 2021. "Analysis of a Bailey–Dietz model for vector-borne disease under regime switching," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 580(C).
    6. Huo, Hai-Feng & Jing, Shuang-Lin & Wang, Xun-Yang & Xiang, Hong, 2020. "Modeling and analysis of a H1N1 model with relapse and effect of Twitter," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 560(C).
    7. Liu, Qun & Jiang, Daqing & Hayat, Tasawar & Alsaedi, Ahmed & Ahmad, Bashir, 2020. "Stationary distribution of a stochastic cholera model between communities linked by migration," Applied Mathematics and Computation, Elsevier, vol. 373(C).
    8. Tian, Baodan & Zhang, Yong & Li, Jiamei, 2020. "Stochastic perturbations for a duopoly Stackelberg model," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 545(C).
    9. Yang, Qian & Huo, Hai-Feng & Xiang, Hong, 2023. "Analysis of an edge-based SEIR epidemic model with sexual and non-sexual transmission routes," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 609(C).
    10. Wang, Weiming & Cai, Yongli & Ding, Zuqin & Gui, Zhanji, 2018. "A stochastic differential equation SIS epidemic model incorporating Ornstein–Uhlenbeck process," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 509(C), pages 921-936.
    11. Han, Cheng & Wang, Yan & Jiang, Daqing, 2023. "Dynamics analysis of a stochastic HIV model with non-cytolytic cure and Ornstein–Uhlenbeck process," Chaos, Solitons & Fractals, Elsevier, vol. 175(P1).
    12. Han, Bingtao & Jiang, Daqing, 2023. "Coexistence and extinction for a stochastic vegetation-water model motivated by Black–Karasinski process," Chaos, Solitons & Fractals, Elsevier, vol. 175(P2).
    13. Lu, Chun & Xu, Chuanlong, 2024. "Dynamic properties for a stochastic SEIR model with Ornstein–Uhlenbeck process," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 216(C), pages 288-300.
    14. Guo, Wenjuan & Zhang, Qimin, 2021. "Explicit numerical approximation for an impulsive stochastic age-structured HIV infection model with Markovian switching," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 182(C), pages 86-115.
    15. Yang, Xiaochen & Yang, Zhanwen & Zhang, Chiping, 2023. "Numerical analysis of the Linearly implicit Euler method with truncated Wiener process for the stochastic SIR model," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 208(C), pages 1-14.
    16. Li, Qiang & Kang, Ting & Zhang, Qimin, 2018. "Mean-square dissipative methods for stochastic age-dependent capital system with fractional Brownian motion and jumps," Applied Mathematics and Computation, Elsevier, vol. 339(C), pages 81-92.
    17. Laaribi, Aziz & Boukanjime, Brahim & El Khalifi, Mohamed & Bouggar, Driss & El Fatini, Mohamed, 2023. "A generalized stochastic SIRS epidemic model incorporating mean-reverting Ornstein–Uhlenbeck process," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 615(C).
    18. Wang, Lei & Wang, Kai & Jiang, Daqing & Hayat, Tasawar, 2018. "Nontrivial periodic solution for a stochastic brucellosis model with application to Xinjiang, China," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 510(C), pages 522-537.
    19. Zou, Xiaoling & Ma, Pengyu & Zhang, Liren & Lv, Jingliang, 2022. "Dynamic properties for a stochastic food chain model," Chaos, Solitons & Fractals, Elsevier, vol. 155(C).
    20. Yang, Bo, 2018. "A stochastic Feline immunodeficiency virus model with vertical transmission," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 509(C), pages 448-458.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:chsofr:v:139:y:2020:i:c:s0960077920304227. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thayer, Thomas R. (email available below). General contact details of provider: https://www.journals.elsevier.com/chaos-solitons-and-fractals .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.