IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v61y2016i6id54-2016-vetmed.html
   My bibliography  Save this article

Effect of sodium humate and zinc oxide used in prophylaxis of post-weaning diarrhoea on faecal microbiota composition in weaned piglets

Author

Listed:
  • M. Kaevska

    (Veterinary Research Institute, Brno, Czech Republic)

  • A. Lorencova

    (Veterinary Research Institute, Brno, Czech Republic)

  • P. Videnska

    (Veterinary Research Institute, Brno, Czech Republic)

  • K. Sedlar

    (Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic)

  • I. Provaznik

    (Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic)

  • M. Trckova

    (Veterinary Research Institute, Brno, Czech Republic)

Abstract

The aim of this study was to use high throughput sequencing of piglet faeces to investigate if the favourable effects of sodium humate (HNa) and zinc oxide (ZnO) in post-weaning diarrhoea (PWD) treatment are related to changes in the faecal microbiota. Twenty four piglets weaned at 28 days of age were divided into three groups with eight animals per pen: a control group without any treatment (Control), a group treated with 2500 mg ZnO (ZnO), and a group treated with 20 g sodium humate and 1700 mg ZnO (HNa + ZnO) per kg of diet. Piglets of all three groups were challenged with two enterotoxigenic Escherichia coli (ETEC) strains (ETEC/O149/F4/LT and ETEC/O147/F18/LT) on Day 4 post-weaning. As a result very intense and severe diarrhoea with high mortality developed in the ETEC-infected control group, while the ZnO and HNa + ZnO dietary treatments both protected piglets from clinical signs of diarrhoea, mortality and depression of growth performance. A higher relative abundance of Gammaproteobacteria represented mainly by genus Escherichia on Day 10 post-weaning in faeces of the ETEC-infected control group in comparison with ZnO and HNa + ZnO was detected. On Day 21, the highest relative increase of beneficial lactobacilli was observed in the HNa + ZnO group. Correlation analysis showed a positive correlation of the ETEC-infected control with the genera Turicibacter, Clostridium, Campylobacter, Dehalobacterium, Desulfuvibrio, Paludibacter and a negative correlation with the genera Prevotella, Blautia, Faecalibacterium, Lactobacillus, and Coprococcus. The opposite correlations with these genera were observed in the supplemented groups, especially in the HNa + ZnO group. The results indicate that dietary supplementation with HNa and ZnO affects the microbial composition of faeces while maintaining good health condition and growth performance of ETEC-infected weaned pigs.

Suggested Citation

  • M. Kaevska & A. Lorencova & P. Videnska & K. Sedlar & I. Provaznik & M. Trckova, 2016. "Effect of sodium humate and zinc oxide used in prophylaxis of post-weaning diarrhoea on faecal microbiota composition in weaned piglets," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 61(6), pages 328-336.
  • Handle: RePEc:caa:jnlvet:v:61:y:2016:i:6:id:54-2016-vetmed
    DOI: 10.17221/54/2016-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/54/2016-VETMED.html
    Download Restriction: free of charge

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/54/2016-VETMED.pdf
    Download Restriction: free of charge

    File URL: https://libkey.io/10.17221/54/2016-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. H. Vondruskova & R. Slamova & M. Trckova & Z. Zraly & I. Pavlik, 2010. "Alternatives to antibiotic growth promoters in prevention of diarrhoea in weaned piglets: a review," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 55(5), pages 199-224.
    2. M. Trckova & A. Lorencova & K. Hazova & Z. Sramkova Zajacova, 2015. "Prophylaxis of post-weaning diarrhoea in piglets by zinc oxide and sodium humate," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 60(7), pages 351-360.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. J. Mazurova & R. Kukla & M. Rozkot & A. Lustykova & E. Slehova & R. Sleha & J. Lipensky & L. Opletal, 2015. "Use of natural substances for boar semen decontamination," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 60(5), pages 235-247.
    2. H. Valpotic & S. Terzic & S. Vince & M. Samardzija & R. Turk & G. Lackovic & B. Habrun & D. Djuricic & M. Sadikovic & I. Valpotic, 2016. "In-feed supplementation of clinoptilolite favourably modulates intestinal and systemic immunity and some production parameters in weaned pigs," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 61(6), pages 317-327.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:61:y:2016:i:6:id:54-2016-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.