IDEAS home Printed from https://ideas.repec.org/a/caa/jnlcjs/v58y2013i1id6519-cjas.html
   My bibliography  Save this article

Effects of vitamin D3 on expression of defensins, Toll-like receptors, and vitamin D receptor in liver, kidney, and spleen of Silky Fowl

Author

Listed:
  • S.M. Li

    (Institute of Animal Husbandry and Veterinary, Jiangxi Academy of Agricultural Science, Nanchang, P.R. China)

  • L.H. Ouyang

    (Institute of Animal Husbandry and Veterinary, Jiangxi Academy of Agricultural Science, Nanchang, P.R. China)

  • D.G. Zhou

    (College of Animal Science and Technology, Sichuan Agricultural University, Yaan, P.R. China)

Abstract

The expression of avian β-defensins (AvBDs), Toll-like receptors (TLRs), and vitamin D receptor (VDR) following in vivo vitamin D3 injection was studied. Healthy 90-day Silky Fowls were abdominally injected with vitamin D3 or untreated. Real-time PCR analyses revealed that injection of vitamin D3 significantly (P < 0.05) up-regulated the expression of TLRs (TLR2, TLR5), VDR, AvBDs (AVBD-6, GAL-1), and 24-hydroxylase (CYP24A1) in the tissues (liver, spleen, and kidney) at various times 8-24 h post injection. These results suggest that expression of VDR, AvBDs, and TLRs seems to be induced by vitamin D3 and it was concluded that the tissues expressing TLRs and VDR respond to vitamin D3 and in turn upregulate these tissues cellular functions to synthesize AvBDs. Intraperitoneal injection of vitamin D3 likely resulted in enhancing the expression of AvBDs, TLRs, and VDR, which providedinsight into factors important for the control of the innateimmune response in the chickens.

Suggested Citation

  • S.M. Li & L.H. Ouyang & D.G. Zhou, 2013. "Effects of vitamin D3 on expression of defensins, Toll-like receptors, and vitamin D receptor in liver, kidney, and spleen of Silky Fowl," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 58(1), pages 1-7.
    • Handle: RePEc:caa:jnlcjs:v:58:y:2013:i:1:id:6519-cjas
    DOI: 10.17221/6519-CJAS
    as

    Download full text from publisher

    File URL: http://cjas.agriculturejournals.cz/doi/10.17221/6519-CJAS.html
    Download Restriction: free of charge
    File URL: http://cjas.agriculturejournals.cz/doi/10.17221/6519-CJAS.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/6519-CJAS?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. K. Bílek & A. Knoll & A. Stratil & K. Svobodová & P. Horák & R. Bechyňová & M. Van Poucke & L.J. Peelman, 2008. "Analysis of mRNA expression of CNN3, DCN, FBN2, POSTN, SPARC and YWHAQ genes in porcine foetal and adult skeletal muscles," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 53(5), pages 181-186.
    2. M. Sezer & S. Tarhan, 2005. "Model parameters of growth curves of three meat-type lines of Japanese quail," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 50(1), pages 22-30.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. J. Baumgartner & Z. Končeková & J. Benková & D. Peškovičová & J. Simenovová & J. Csuka, 2008. "Changes in egg quality traits associated with long-term selection for lower yolk cholesterol content in Japanese quail," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 53(3), pages 119-127.
    2. Liu Yongganmg & Gao Shizheng, 2010. "A novel porcine gene, USP7, differentially expressed in the musculus longissimus from Wujin and Large White pigs," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 55(1), pages 37-41.

    More about this item

    Keywords

    vitamin D3; induction; chicken; avian β -defensins; real-time PCR;
    All these keywords.

    JEL classification:

    • D3 - Microeconomics - - Distribution

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlcjs:v:58:y:2013:i:1:id:6519-cjas. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.