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Discussion on “Predictively consistent prior effective sample sizes,” by Beat Neuenschwander, Sebastian Weber, Heinz Schmidli, and Anthony O'Hagan

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  • Atanu Biswas
  • Jean‐François Angers

Abstract

We extend the approach of finding effective sample size for a typical phase II clinical trial having efficacy and toxicity as two components of the response vector. The case of binary efficacy and binary toxicity is illustrated under Dirichlet and multivariate T priors.

Suggested Citation

  • Atanu Biswas & Jean‐François Angers, 2020. "Discussion on “Predictively consistent prior effective sample sizes,” by Beat Neuenschwander, Sebastian Weber, Heinz Schmidli, and Anthony O'Hagan," Biometrics, The International Biometric Society, vol. 76(2), pages 591-594, June.
    • Handle: RePEc:bla:biomet:v:76:y:2020:i:2:p:591-594
    DOI: 10.1111/biom.13247
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    1. Beat Neuenschwander & Sebastian Weber & Heinz Schmidli & Anthony O'Hagan, 2020. "Predictively consistent prior effective sample sizes," Biometrics, The International Biometric Society, vol. 76(2), pages 578-587, June.
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