IDEAS home Printed from https://ideas.repec.org/a/aph/ajpbhl/10.2105-ajph.2013.301252_0.html
   My bibliography  Save this article

Critical need for family-based, quasi-experimental designs in integrating genetic and social science research

Author

Listed:
  • D'Onofrio, B.M.
  • Lahey, B.B.
  • Turkheimer, E.
  • Lichtenstein, P.

Abstract

Researchers have identified environmental risks that predict subsequent psychological and medical problems. Based on these correlational findings, researchers have developed and tested complex developmental models and have examined biological moderating factors (e.g., gene- environment interactions). In this context, we stress the critical need for researchers to use familybased, quasi-experimental designs when trying to integrate genetic and social science research involving environmental variables because these designs rigorously examine causal inferences by testing competing hypotheses. We argue that sibling comparison, offspring of twins or siblings, in vitro fertilization designs, and other genetically informed approaches play a unique role in bridging gaps between basic biological and social science research. We use studies on maternal smoking during pregnancy to exemplify these principles.

Suggested Citation

  • D'Onofrio, B.M. & Lahey, B.B. & Turkheimer, E. & Lichtenstein, P., 2013. "Critical need for family-based, quasi-experimental designs in integrating genetic and social science research," American Journal of Public Health, American Public Health Association, vol. 103(SUPPL.1), pages 46-55.
  • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301252_0
    DOI: 10.2105/AJPH.2013.301252
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.2105/AJPH.2013.301252
    Download Restriction: no

    File URL: https://libkey.io/10.2105/AJPH.2013.301252?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ragnhild E Brandlistuen & Eivind Ystrom & Sonia Hernandez-Diaz & Svetlana Skurtveit & Randi Selmer & Marte Handal & Hedvig Nordeng, 2017. "Association of prenatal exposure to benzodiazepines and child internalizing problems: A sibling-controlled cohort study," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-16, July.
    2. Elizabeth Wall-Wieler & Leslie L. Roos & Dan Chateau & Noralou P. Roos, 2018. "Social Context of Welfare in Manitoba, Canada," Social Indicators Research: An International and Interdisciplinary Journal for Quality-of-Life Measurement, Springer, vol. 135(2), pages 661-682, January.
    3. Chen, Juan & Chen, Xi & Leung, Samuel S.M. & Tsang, Hector W.H., 2021. "Potential impacts, alleviating factors, and interventions for children of a parent with schizophrenia: A scoping review," Children and Youth Services Review, Elsevier, vol. 120(C).
    4. Felix C. Tropf & Jornt J. Mandemakers, 2017. "Is the Association Between Education and Fertility Postponement Causal? The Role of Family Background Factors," Demography, Springer;Population Association of America (PAA), vol. 54(1), pages 71-91, February.
    5. Silvia H. Barcellos & Leandro Carvalho & Patrick Turley, 2021. "The Effect of Education on the Relationship between Genetics, Early-Life Disadvantages, and Later-Life SES," NBER Working Papers 28750, National Bureau of Economic Research, Inc.
    6. Jackson, Dylan B., 2016. "The link between poor quality nutrition and childhood antisocial behavior: A genetically informative analysis," Journal of Criminal Justice, Elsevier, vol. 44(C), pages 13-20.
    7. Kateřina Nezvalová-Henriksen & Mollie Wood & Olav Spigset & Hedvig Nordeng, 2016. "Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-15, December.
    8. Tropf, Felix C & Mandemakers, Jornt J, 2017. "Is the Association Between Education and Fertility Postponement Causal? The Role of Family Background Factors," OSF Preprints dqrrx, Center for Open Science.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301252_0. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://www.apha.org .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.