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Zymosan A, an Old Tool in Experimental Pharmacology with Newer Applications

Author

Listed:
  • Ravinder Naik Dharavath

    (Pharmacology Research Laboratory, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India)

  • Vibhu Kumar

    (Pharmacology Research Laboratory, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India)

  • Vibhu Kumar

    (Pharmacology Research Laboratory, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India)

Abstract

Insulin resistance (IR) is an important link between obesity and post obesity complications varying from diabetes mellitus to neurological insults such as cognitive dysfunction and Alzheimer’s disease. Currently available high calorific diet induced preclinical models mimic clinical pathologies of various metabolic disorders but they are highly time consuming. Zymosan A, a well-known inflammagen has recently been used to induce reversible IR conditions in rodent models.

Suggested Citation

  • Ravinder Naik Dharavath & Vibhu Kumar & Vibhu Kumar, 2017. "Zymosan A, an Old Tool in Experimental Pharmacology with Newer Applications," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 4(3), pages 58-61, October.
    • Handle: RePEc:adp:jcrdoj:v:4:y:2017:i:3:p:58-61
    DOI: 10.19080/CRDOJ.2017.04.555638
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    References listed on IDEAS

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    1. Steven E. Kahn & Rebecca L. Hull & Kristina M. Utzschneider, 2006. "Mechanisms linking obesity to insulin resistance and type 2 diabetes," Nature, Nature, vol. 444(7121), pages 840-846, December.
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    More about this item

    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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