IDEAS home Printed from https://ideas.repec.org/p/wop/iasawp/ir98096.html
   My bibliography  Save this paper

The Evolutionary Ecology of Dominance-Recessivity

Author

Listed:
  • T.J.M. van Dooren

Abstract

An "adaptive dynamics" modeling approach to the evolution of dominance-recessivity is presented. In this approach fitness derives from an explicit ecological scenario. The ecology consists of a within-individual part presenting a locus with regulated activity, and a between-individual part that is a two-patch soft selection model. Evolutionary freedom is allowed at a single locus. The evolutionary analysis considers directed random walks on trait space, generated by invasions of mutants. The phenotype of an individual is determined by allelic parameters. Mutations can have two effects: they either affect the affinity of the promoter sequence for transcription factors, or they affect the gene product. The dominance interaction between alleles derives from their promoter affinities. I show by means of an example that additive genetics is evolutionarily unstable when selection and evolution maintain two alleles in the population. In such a situation, dominance interactions can become stationary close to additive genetics or they continue to evolve at a very slow pace towards dominance-recessivity. The probability that a specific dominance interaction will evolve depends on the relative mutation rate of promoter compared to gene product and the distribution of mutational effect sizes. Either of both alleles in the dimorphism can become dominant and dominance-recessivity is always most likely to evolve. Evolution then approaches a population state where every phenotype in the population has a maximum viability in one of the two patches. When the within-individual part is replaced by a housekeeping locus that codes for a metabolic enzyme, evolution favors a population of two alleles on the same conditions as for a regulated locus. In the case of housekeeping gene however, the evolutionary dynamics is attracted towards a population state where the heterozygote phenotype equal the optimum phenotypes in the two patches.

Suggested Citation

  • T.J.M. van Dooren, 1998. "The Evolutionary Ecology of Dominance-Recessivity," Working Papers ir98096, International Institute for Applied Systems Analysis.
    • Handle: RePEc:wop:iasawp:ir98096
    as

    Download full text from publisher

    File URL: http://www.iiasa.ac.at/Publications/Documents/IR-98-096.pdf
    Download Restriction: no
    File URL: http://www.iiasa.ac.at/Publications/Documents/IR-98-096.ps
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Mark Ptashne & Alexander Gann, 1997. "Transcriptional activation by recruitment," Nature, Nature, vol. 386(6625), pages 569-577, April.
    2. U. Dieckmann & R. Law, 1996. "The Dynamical Theory of Coevolution: A Derivation from Stochastic Ecological Processes," Working Papers wp96001, International Institute for Applied Systems Analysis.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Nassar, Elma & Pardoux, Etienne, 2019. "Small jumps asymptotic of the moving optimum Poissonian SDE," Stochastic Processes and their Applications, Elsevier, vol. 129(7), pages 2320-2340.
    2. Till D Frank & Aimée M Carmody & Boris N Kholodenko, 2012. "Versatility of Cooperative Transcriptional Activation: A Thermodynamical Modeling Analysis for Greater-Than-Additive and Less-Than-Additive Effects," PLOS ONE, Public Library of Science, vol. 7(4), pages 1-15, April.
    3. Joëlle Noailly, 2008. "Coevolution of economic and ecological systems," Journal of Evolutionary Economics, Springer, vol. 18(1), pages 1-29, February.
    4. Alistair N Boettiger & Peter L Ralph & Steven N Evans, 2011. "Transcriptional Regulation: Effects of Promoter Proximal Pausing on Speed, Synchrony and Reliability," PLOS Computational Biology, Public Library of Science, vol. 7(5), pages 1-14, May.
    5. Åke Brännström & Jacob Johansson & Niels Von Festenberg, 2013. "The Hitchhiker’s Guide to Adaptive Dynamics," Games, MDPI, vol. 4(3), pages 1-25, June.
    6. Nonaka, Etsuko & Kuparinen, Anna, 2023. "Limited effects of size-selective harvesting and harvesting-induced life-history changes on the temporal variability of biomass dynamics in complex food webs," Ecological Modelling, Elsevier, vol. 476(C).
    7. Cressman, Ross & Hofbauer, Josef & Riedel, Frank, 2005. "Stability of the Replicator Equation for a Single-Species with a Multi-Dimensional Continuous Trait Space," Bonn Econ Discussion Papers 12/2005, University of Bonn, Bonn Graduate School of Economics (BGSE).
    8. Peña, Jorge & González-Forero, Mauricio, 2020. "Eusociality through conflict dissolution via maternal reproductive specialization," IAST Working Papers 20-110, Institute for Advanced Study in Toulouse (IAST).
    9. Boettiger, Carl & Dushoff, Jonathan & Weitz, Joshua S., 2010. "Fluctuation domains in adaptive evolution," Theoretical Population Biology, Elsevier, vol. 77(1), pages 6-13.
    10. Dercole, Fabio & Prieu, Charlotte & Rinaldi, Sergio, 2010. "Technological change and fisheries sustainability: The point of view of Adaptive Dynamics," Ecological Modelling, Elsevier, vol. 221(3), pages 379-387.
    11. U. Dieckmann & M. Doebeli, 1999. "On the Origin of Species by Sympatric Speciation," Working Papers ir99013, International Institute for Applied Systems Analysis.
    12. Svardal, Hannes & Rueffler, Claus & Hermisson, Joachim, 2015. "A general condition for adaptive genetic polymorphism in temporally and spatially heterogeneous environments," Theoretical Population Biology, Elsevier, vol. 99(C), pages 76-97.
    13. Krishanpal Anamika & Àkos Gyenis & Laetitia Poidevin & Olivier Poch & Làszlò Tora, 2012. "RNA Polymerase II Pausing Downstream of Core Histone Genes Is Different from Genes Producing Polyadenylated Transcripts," PLOS ONE, Public Library of Science, vol. 7(6), pages 1-14, June.
    14. Hammerstein, Peter & Leimar, Olof, 2015. "Evolutionary Game Theory in Biology," Handbook of Game Theory with Economic Applications,, Elsevier.
    15. Durrett, Rick & Mayberry, John, 2010. "Evolution in predator-prey systems," Stochastic Processes and their Applications, Elsevier, vol. 120(7), pages 1364-1392, July.
    16. Lala M Motlhabi & Gary D Stormo, 2011. "Assessing the Effects of Symmetry on Motif Discovery and Modeling," PLOS ONE, Public Library of Science, vol. 6(9), pages 1-8, September.
    17. Johansson, Jacob & Ripa, Jörgen & Kuckländer, Nina, 2010. "The risk of competitive exclusion during evolutionary branching: Effects of resource variability, correlation and autocorrelation," Theoretical Population Biology, Elsevier, vol. 77(2), pages 95-104.
    18. Champagnat, Nicolas, 2006. "A microscopic interpretation for adaptive dynamics trait substitution sequence models," Stochastic Processes and their Applications, Elsevier, vol. 116(8), pages 1127-1160, August.
    19. Michael E Wall & David A Markowitz & Judah L Rosner & Robert G Martin, 2009. "Model of Transcriptional Activation by MarA in Escherichia coli," PLOS Computational Biology, Public Library of Science, vol. 5(12), pages 1-11, December.
    20. Hernán Darío Toro-Zapata & Gerard Olivar-Tost, 2018. "Mathematical Model For The Evolutionary Dynamic Of Innovation In City Public Transport Systems," Copernican Journal of Finance & Accounting, Uniwersytet Mikolaja Kopernika, vol. 7(2), pages 77-98.

    More about this item

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:wop:iasawp:ir98096. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thomas Krichel (email available below). General contact details of provider: https://edirc.repec.org/data/iiasaat.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.