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Covariate Adjustment in Stratified Experiments

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  • Max Cytrynbaum

Abstract

This paper studies covariate adjusted estimation of the average treatment effect in stratified experiments. We work in a general framework that includes matched tuples designs, coarse stratification, and complete randomization as special cases. Regression adjustment with treatment-covariate interactions is known to weakly improve efficiency for completely randomized designs. By contrast, we show that for stratified designs such regression estimators are generically inefficient, potentially even increasing estimator variance relative to the unadjusted benchmark. Motivated by this result, we derive the asymptotically optimal linear covariate adjustment for a given stratification. We construct several feasible estimators that implement this efficient adjustment in large samples. In the special case of matched pairs, for example, the regression including treatment, covariates, and pair fixed effects is asymptotically optimal. We also provide novel asymptotically exact inference methods that allow researchers to report smaller confidence intervals, fully reflecting the efficiency gains from both stratification and adjustment. Simulations and an empirical application demonstrate the value of our proposed methods.

Suggested Citation

  • Max Cytrynbaum, 2023. "Covariate Adjustment in Stratified Experiments," Papers 2302.03687, arXiv.org, revised Jul 2024.
  • Handle: RePEc:arx:papers:2302.03687
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    References listed on IDEAS

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    1. Federico A. Bugni & Ivan A. Canay & Azeem M. Shaikh, 2018. "Inference Under Covariate-Adaptive Randomization," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 113(524), pages 1784-1796, October.
    2. Jinyong Hahn, 1998. "On the Role of the Propensity Score in Efficient Semiparametric Estimation of Average Treatment Effects," Econometrica, Econometric Society, vol. 66(2), pages 315-332, March.
    3. Alberto Abadie & Guido W. Imbens, 2008. "Estimation of the Conditional Variance in Paired Experiments," Annals of Economics and Statistics, GENES, issue 91-92, pages 175-187.
    4. Akanksha Negi & Jeffrey M. Wooldridge, 2021. "Revisiting regression adjustment in experiments with heterogeneous treatment effects," Econometric Reviews, Taylor & Francis Journals, vol. 40(5), pages 504-534, April.
    5. Amy Finkelstein & Sarah Taubman & Bill Wright & Mira Bernstein & Jonathan Gruber & Joseph P. Newhouse & Heidi Allen & Katherine Baicker, 2012. "The Oregon Health Insurance Experiment: Evidence from the First Year," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 127(3), pages 1057-1106.
    6. repec:adr:anecst:y:2008:i:91-92:p:09 is not listed on IDEAS
    7. Colin B Fogarty, 2018. "Regression-assisted inference for the average treatment effect in paired experiments," Biometrika, Biometrika Trust, vol. 105(4), pages 994-1000.
    8. Imbens,Guido W. & Rubin,Donald B., 2015. "Causal Inference for Statistics, Social, and Biomedical Sciences," Cambridge Books, Cambridge University Press, number 9780521885881, September.
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    Cited by:

    1. Yuehao Bai & Hongchang Guo & Azeem M. Shaikh & Max Tabord-Meehan, 2023. "Inference in Experiments with Matched Pairs and Imperfect Compliance," Papers 2307.13094, arXiv.org, revised Jun 2024.
    2. Bai, Yuehao & Jiang, Liang & Romano, Joseph P. & Shaikh, Azeem M. & Zhang, Yichong, 2024. "Covariate adjustment in experiments with matched pairs," Journal of Econometrics, Elsevier, vol. 241(1).
    3. Max Cytrynbaum, 2024. "Finely Stratified Rerandomization Designs," Papers 2407.03279, arXiv.org, revised Jul 2024.
    4. Liang Jiang & Liyao Li & Ke Miao & Yichong Zhang, 2023. "Adjustment with Many Regressors Under Covariate-Adaptive Randomizations," Papers 2304.08184, arXiv.org, revised Nov 2024.

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