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POWER_DIAGNOSTIC: Stata module to compute power and sample size for sensitivity and specificity of a diagnostic test

Author

Listed:
  • Ariel Linden

    (Linden Consulting Group, LLC)

Programming Language

Stata

Abstract

The power diagnostic suite of commands is useful for planning prospective studies evaluating the accuracy of diagnostic tests for a binary outcome (e.g. diseased/not-diseased) and in which a test's sensitivity and specificity are the measures of interest. Sensitivity is the probability of a test detecting disease when the patient actually has the disease, and specificity is the probability that the test is negative when the patient is actually disease-free. Sample size and power can be computed for a one-sample, two-sample, and paired-sample diagnostic test. All power diagnostic commands implement the naive prevalence inflation method introduced by Obuchowski and Zhou (2002). Li and Fine (2004) found this method (which they refer to as "Method 0") to be a useful approximation to exact sample-size calculations based on unconditional power, which are more computationally intensive. Sample size can be computed given power, and power can be computed given sample size. Results can be displayed in a table (default) and on a graph ([PSS-2] power, graph).

Suggested Citation

  • Ariel Linden, 2022. "POWER_DIAGNOSTIC: Stata module to compute power and sample size for sensitivity and specificity of a diagnostic test," Statistical Software Components S459116, Boston College Department of Economics.
    • Handle: RePEc:boc:bocode:s459116
    Note: This module should be installed from within Stata by typing "ssc install power_diagnostic". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_onesens_init.ado
    File Function: program code
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_onesens.ado
    File Function: program code
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_onesens.sthlp
    File Function: help file
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_onespec_init.ado
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_onespec.ado
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_onespec.sthlp
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_pairsens_init.ado
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_cmd_twosens_init.ado
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    File URL: http://fmwww.bc.edu/repec/bocode/p/power_diagnostic.sthlp
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