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SENTINEL: Stata module for selecting sentinel variants from SNPs in a case-control study

Author

Listed:
  • William D. Dupont

    (Vanderbilt University School of Medicine)

  • W. Dale Plummer, Jr.

    (Vanderbilt University School of Medicine)

  • Jeffrey R. Smith

    (Vanderbilt University Medical Center)

Programming Language

Stata

Abstract

sentinel selects sentinel SNPs from the genetic variants in indepvars. These are SNPs that best detect independent risk-altering signals. In a multivariable multiplicative logistic regression model that regresses depvar against the sentinel variants, each variant is significantly associated with depvar and the absolute value of the correlation coefficient of each pair of variants is low.

Suggested Citation

  • William D. Dupont & W. Dale Plummer, Jr. & Jeffrey R. Smith, 2020. "SENTINEL: Stata module for selecting sentinel variants from SNPs in a case-control study," Statistical Software Components S458746, Boston College Department of Economics, revised 03 Apr 2020.
    • Handle: RePEc:boc:bocode:s458746
    Note: This module should be installed from within Stata by typing "ssc install sentinel". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
    as

    Download full text from publisher

    File URL: http://fmwww.bc.edu/repec/bocode/s/sentinel.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/s/sentinel.sthlp
    File Function: help file
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/t/TestSNPs.do
    File Function: sample do file
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/t/TestSNPs.dta
    File Function: sample data file
    Download Restriction: no
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