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Lattice Boltzmann Modeling Of Thrombosis In Giant Aneurysms

Author

Listed:
  • B. CHOPARD

    (CUI, University of Geneva, 24 rue General-Dufour, 1211 Geneva 4, Switzerland)

  • R. OUARED

    (CUI, University of Geneva, 24 rue General-Dufour, 1211 Geneva 4, Switzerland)

  • D. A. RUEFENACHT

    (Neuroradiology, HUG, 24 rue Micheli-du-Crest, 1211 Geneva 4, Switzerland)

  • H. YILMAZ

    (Neuroradiology, HUG, 24 rue Micheli-du-Crest, 1211 Geneva 4, Switzerland)

Abstract

We propose a numerical model of blood flow and blood clotting whose purpose is to describe thrombus formation in cerebral aneurysms. We identify possible mechanisms that can cause occurence of spontaneous thrombosis in unruptured giant intracranial aneurysms. Our main claim is that, under normal conditions, there is a low shear rate threshold below which thrombosis starts and growths. This assumption is supported by several evidences from literature. The proposed mechanisms are incorporated into a Lattice Boltzmann (LB) model for blood flow and platelets adhesion and aggregation. Numerical simulations show that the low shear rate threshold assumption together with aneurysm geometry account well for the observations.

Suggested Citation

  • B. Chopard & R. Ouared & D. A. Ruefenacht & H. Yilmaz, 2007. "Lattice Boltzmann Modeling Of Thrombosis In Giant Aneurysms," International Journal of Modern Physics C (IJMPC), World Scientific Publishing Co. Pte. Ltd., vol. 18(04), pages 712-721.
    • Handle: RePEc:wsi:ijmpcx:v:18:y:2007:i:04:n:s0129183107010978
    DOI: 10.1142/S0129183107010978
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    References listed on IDEAS

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