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A combination of experimental measurement, constitutive damage model, and diffusion tensor imaging to characterize the mechanical properties of the human brain

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  • Alireza Karimi
  • Seyed Mohammadali Rahmati
  • Reza Razaghi

Abstract

Understanding the mechanical properties of the human brain is deemed important as it may subject to various types of complex loadings during the Traumatic Brain Injury (TBI). Although many studies so far have been conducted to quantify the mechanical properties of the brain, there is a paucity of knowledge on the mechanical properties of the human brain tissue and the damage of its axon fibers under the various types of complex loadings during the Traumatic Brain Injury (TBI). Although many studies so far have been conducted to quantify the mechanical properties of the brain, there is a paucity of knowledge on the mechanical properties of the human brain tissue and the damage of its axon fibers under the frontal lobe of the human brain. The constrained nonlinear minimization method was employed to identify the brain coefficients according to the axial and transversal compressive data. The pseudo-elastic damage model data was also well compared with that of the experimental data and it not only up to the primary loading but also the discontinuous softening could well address the mechanical behavior of the brain tissue.

Suggested Citation

  • Alireza Karimi & Seyed Mohammadali Rahmati & Reza Razaghi, 2017. "A combination of experimental measurement, constitutive damage model, and diffusion tensor imaging to characterize the mechanical properties of the human brain," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 20(12), pages 1350-1363, September.
  • Handle: RePEc:taf:gcmbxx:v:20:y:2017:i:12:p:1350-1363
    DOI: 10.1080/10255842.2017.1362694
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    References listed on IDEAS

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    1. B.K. Wicker & H.P. Hutchens & Q. Wu & A.T. Yeh & J.D. Humphrey, 2008. "Normal basilar artery structure and biaxial mechanical behaviour," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 11(5), pages 539-551.
    2. Zhen Ma & João Manuel R.S. Tavares & Renato Natal Jorge & T. Mascarenhas, 2010. "A review of algorithms for medical image segmentation and their applications to the female pelvic cavity," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 13(2), pages 235-246.
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