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Validation of numerical flow simulations against phantom measurements in different type B aortic dissection scenarios

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Listed:
  • Eduardo Soudah
  • Paula Rudenick
  • Maurizio Bordone
  • Bart Bijnens
  • David García-Dorado
  • Arturo Evangelista
  • Eugenio Oñate

Abstract

An aortic dissection (AD) is a serious condition defined by the splitting of the arterial wall, thus generating a secondary lumen [the false lumen (FL)]. Its management, treatment and follow-up are clinical challenges due to the progressive aortic dilatation and potentially severe complications during follow-up. It is well known that the direction and rate of dilatation of the artery wall depend on haemodynamic parameters such as the local velocity profiles, intra-luminal pressures and resultant wall stresses. These factors act on the FL and true lumen, triggering remodelling and clinical worsening. In this study, we aimed to validate a computational fluid dynamic (CFD) tool for the haemodynamic characterisation of chronic (type B) ADs. We validated the numerical results, for several dissection geometries, with experimental data obtained from a previous in vitro study performed on idealised dissected physical models. We found a good correlation between CFD simulations and experimental measurements as long as the tear size was large enough so that the effect of the wall compliance was negligible.

Suggested Citation

  • Eduardo Soudah & Paula Rudenick & Maurizio Bordone & Bart Bijnens & David García-Dorado & Arturo Evangelista & Eugenio Oñate, 2015. "Validation of numerical flow simulations against phantom measurements in different type B aortic dissection scenarios," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 18(8), pages 805-815, June.
    • Handle: RePEc:taf:gcmbxx:v:18:y:2015:i:8:p:805-815
    DOI: 10.1080/10255842.2013.847095
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    Cited by:

    1. Paula A Rudenick & Bart H Bijnens & Patrick Segers & David García-Dorado & Arturo Evangelista, 2015. "Assessment of Wall Elasticity Variations on Intraluminal Haemodynamics in Descending Aortic Dissections Using a Lumped-Parameter Model," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-17, April.
    2. Pavel B Ryzhakov, 2019. "On the Relevance of Accounting for Uid-Structure Interaction E Ects in the Numerical Studies of Type B Aortic Dissection," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 16(3), pages 12039-12042, March.

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