Determinants of biopharmaceutical R&D expenditures in China: the impact of spatiotemporal context
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DOI: 10.1007/s11192-021-04058-y
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- Sheng-qiang Jiang & An-na Shi & Zhi-hang Peng & Xin Li, 2017. "Major factors affecting cross-city R&D collaborations in China: evidence from cross-sectional co-patent data between 224 cities," Scientometrics, Springer;Akadémiai Kiadó, vol. 111(3), pages 1251-1266, June.
- Iain M. Cockburn & Matthew J. Slaughter, 2010.
"The Global Location of Biopharmaceutical Knowledge Activity: New Findings, New Questions,"
Innovation Policy and the Economy, University of Chicago Press, vol. 10(1), pages 129-157.
- Iain M. Cockburn & Matthew J. Slaughter, 2010. "The Global Location of Biopharmaceutical Knowledge Activity: New Findings, New Questions," NBER Chapters, in: Innovation Policy and the Economy, Volume 10, pages 129-157, National Bureau of Economic Research, Inc.
- Wang, Eric C., 2010. "Determinants of R&D investment: The Extreme-Bounds-Analysis approach applied to 26 OECD countries," Research Policy, Elsevier, vol. 39(1), pages 103-116, February.
- Goel, Rajeev K. & Haruna, Shoji, 2007. "Cooperative and noncooperative R&D with spillovers: The case of labor-managed firms," Economic Systems, Elsevier, vol. 31(4), pages 423-440, December.
- M. Breton & A. Turki & G. Zaccour, 2004. "Dynamic Model of R&D, Spillovers, and Efficiency of Bertrand and Cournot Equilibria," Journal of Optimization Theory and Applications, Springer, vol. 123(1), pages 1-25, October.
- Smrkolj, Grega & Wagener, Florian, 2016. "Dynamic R&D with spillovers: A comment," Journal of Economic Dynamics and Control, Elsevier, vol. 73(C), pages 453-457.
- Satoshi Hayashi & Naoki Tsuge, 2019. "Necessary and sufficient condition for equilibrium of the Hotelling model," Papers 1907.06200, arXiv.org.
- Tsai-Ling Liao & Wen-Chun Lin, 2017. "Corporate Governance, Product Market Competition, and the Wealth Effect of R&D Spending Changes," Financial Management, Financial Management Association International, vol. 46(3), pages 717-742, September.
- Cellini, Roberto & Lambertini, Luca, 2009.
"Dynamic R&D with spillovers: Competition vs cooperation,"
Journal of Economic Dynamics and Control, Elsevier, vol. 33(3), pages 568-582, March.
- R. Cellini & L. Lambertini, 2003. "Dynamic R&D with Spillovers: Competition vs Cooperation," Working Papers 495, Dipartimento Scienze Economiche, Universita' di Bologna.
- Dolores Añón Higón & Miguel Manjón Antolín & Juan A. Mañez, 2011.
"Multinationals, R&D, and productivity: evidence for UK manufacturing firms,"
Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 20(2), pages 641-659, April.
- Dolores Añon Higon & Miguel Manjon Antolin & Juan A. Mañez, 2010. "Multinationals, R&D and productivity: Evidence for UK Manufacturing firms," Discussion Papers in Economic Behaviour 1110, University of Valencia, ERI-CES.
- Añón Higón, Dolores & Manjón Antolín, Miguel C. & Máñez, Juan A., 2010. "Multinationals, R&D and productivity: Evidence for UK Manufactoring firms," Working Papers 2072/151616, Universitat Rovira i Virgili, Department of Economics.
- Gamble, John E., 2000. "Management commitment to innovation and esop stock concentration," Journal of Business Venturing, Elsevier, vol. 15(5-6), pages 433-447.
- Changying Li & Jianhu Zhang, 2013. "Dynamic Games of R&D Competition in a Differentiated Duopoly," Journal of Institutional and Theoretical Economics (JITE), Mohr Siebeck, Tübingen, vol. 169(4), pages 660-679, December.
- Joseph Golec & John Vernon, 2010. "Financial Effects of Pharmaceutical Price Regulation on R&D Spending by EU versus US Firms," PharmacoEconomics, Springer, vol. 28(8), pages 615-628, August.
- Dong, Jing & Gou, Yan-nan, 2010. "Corporate governance structure, managerial discretion, and the R&D investment in China," International Review of Economics & Finance, Elsevier, vol. 19(2), pages 180-188, April.
- Luigi Orsenigo & Fabio Pammolli & Massimo Riccaboni & Andrea Bonaccorsi & Giuseppe Turchetti, 1997. "The Evolution of Knowledge and the Dynamics of an Industry Network," Journal of Management & Governance, Springer;Accademia Italiana di Economia Aziendale (AIDEA), vol. 1(2), pages 147-175, June.
- Marino, Marianna & Lhuillery, Stephane & Parrotta, Pierpaolo & Sala, Davide, 2016.
"Additionality or crowding-out? An overall evaluation of public R&D subsidy on private R&D expenditure,"
Research Policy, Elsevier, vol. 45(9), pages 1715-1730.
- Marianna Marino & Stéphane Lhuillery & Pierpaolo Parrotta & Davide Sala, 2016. "Additionality or crowding-out ? An overall evaluation of public R&D subsidy on private R&D expenditure," Post-Print hal-01507979, HAL.
- René Belderbos & Elissavet Lykogianni & Reinhilde Veugelers, 2008.
"Strategic R&D Location by Multinational Firms: Spillovers, Technology Sourcing, and Competition,"
Journal of Economics & Management Strategy, Wiley Blackwell, vol. 17(3), pages 759-779, September.
- Veugelers, Reinhilde & Belderbos, René & Lykogianni, Elissavet, 2005. "Strategic R&D Location by Multinational Firms: Spillovers, Technology Sourcing and Competition," CEPR Discussion Papers 5060, C.E.P.R. Discussion Papers.
- Hyunseog Chung & Soomin Eum & Chulung Lee, 2019. "Firm Growth and R&D in the Korean Pharmaceutical Industry," Sustainability, MDPI, vol. 11(10), pages 1-19, May.
- Matsumura, Toshihiro & Matsushima, Noriaki, 2012. "Welfare properties of strategic R&D investments in Hotelling models," Economics Letters, Elsevier, vol. 115(3), pages 465-468.
- Choi, Joonhwan & Lee, Jaegul, 2017. "Repairing the R&D market failure: Public R&D subsidy and the composition of private R&D," Research Policy, Elsevier, vol. 46(8), pages 1465-1478.
- Rachel Hilliard & David Jacobson, 2011. "Cluster versus Firm-specific Factors in the Development of Dynamic Capabilities in the Pharmaceutical Industry in Ireland: A Study of Responses to Changes in Environmental Protection Regulations," Regional Studies, Taylor & Francis Journals, vol. 45(10), pages 1319-1328, November.
- McCutchen, William Jr., 1993. "Estimating the impact of the R&D tax credit on strategic groups in the pharmaceutical industry," Research Policy, Elsevier, vol. 22(4), pages 337-351, August.
- Cabrer-Borras, Bernardi & Serrano-Domingo, Guadalupe, 2007. "Innovation and R&D spillover effects in Spanish regions: A spatial approach," Research Policy, Elsevier, vol. 36(9), pages 1357-1371, November.
- Hudgens, Michael G. & Halloran, M. Elizabeth, 2008. "Toward Causal Inference With Interference," Journal of the American Statistical Association, American Statistical Association, vol. 103, pages 832-842, June.
- Calvin Atewamba & Bruno Nkuiya, 2017. "Testing the Assumptions and Predictions of the Hotelling Model," Environmental & Resource Economics, Springer;European Association of Environmental and Resource Economists, vol. 66(1), pages 169-203, January.
- Satoshi Hayashi & Naoki Tsuge, 2019. "Necessary and sufficient condition for equilibrium of the Hotelling model on a circle," Papers 1910.11154, arXiv.org, revised Oct 2019.
- Beñat Bilbao‐Osorio & Andrés Rodríguez‐Pose, 2004. "From R&D to Innovation and Economic Growth in the EU," Growth and Change, Wiley Blackwell, vol. 35(4), pages 434-455, September.
- Jiafeng Gu, 2021. "Spatial Dynamics between Firm Sales and Environmental Responsibility: The Mediating Role of Corporate Innovation," Sustainability, MDPI, vol. 13(4), pages 1-18, February.
- Bryan P. Schmutz & Rexford E. Santerre, 2013. "Examining The Link Between Cash Flow, Market Value, And Research And Development Investment Spending In The Medical Device Industry," Health Economics, John Wiley & Sons, Ltd., vol. 22(2), pages 157-167, February.
- Nightingale, Paul, 2000. "Economies of Scale in Experimentation: Knowledge and Technology in Pharmaceutical R&D," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 9(2), pages 315-359, June.
- André Spithoven & Peter Teirlinck, 2002. "The spatial dimension of the R&D expenditures in the Belgian enterprise sector," Brussels Economic Review, ULB -- Universite Libre de Bruxelles, vol. 45(4), pages 157-186.
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Cited by:
- Jiafeng Gu, 2021. "Effects of Patent Policy on Outputs and Commercialization of Academic Patents in China: A Spatial Difference-in-Differences Analysis," Sustainability, MDPI, vol. 13(23), pages 1-17, December.
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Keywords
R&D; Spatiotemporal content; Spatial spillover; Pharmaceuticals; China;All these keywords.
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