IDEAS home Printed from https://ideas.repec.org/a/spr/ijphth/v62y2017i7d10.1007_s00038-017-0993-2.html
   My bibliography  Save this article

Impact of preventable risk factors on stroke in the EPICOR study: does gender matter?

Author

Listed:
  • Slavica Trajkova

    (University of Turin and Città della Salute e della Scienza University-Hospital Center for Cancer Prevention (CPO))

  • Angelo d’Errico

    (Regional Health Service)

  • Fulvio Ricceri

    (University of Turin and Città della Salute e della Scienza University-Hospital Center for Cancer Prevention (CPO)
    Regional Health Service)

  • Francesca Fasanelli

    (University of Turin and Città della Salute e della Scienza University-Hospital Center for Cancer Prevention (CPO))

  • Valeria Pala

    (Fondazione IRCCS Istituto Nazionale dei Tumori)

  • Claudia Agnoli

    (Fondazione IRCCS Istituto Nazionale dei Tumori)

  • Rosario Tumino

    (Cancer Registry, Department of Prevention)

  • Graziella Frasca

    (Cancer Registry, Department of Prevention)

  • Giovanna Masala

    (Cancer Risk Factors and Lifestyle Epidemiology Unit Cancer Research and Prevention Institute-ISPO)

  • Calogero Saieva

    (Cancer Risk Factors and Lifestyle Epidemiology Unit Cancer Research and Prevention Institute-ISPO)

  • Paolo Chiodini

    (Second University of Naples)

  • Amalia Mattiello

    (Federico II University)

  • Carlotta Sacerdote

    (University of Turin and Città della Salute e della Scienza University-Hospital Center for Cancer Prevention (CPO))

  • Salvatore Panico

    (Federico II University)

Abstract

Objectives The effect of modifiable stroke risk factors in terms of prevented cases remains unclear due to sex-specific disease rate and risk factors prevalence. Our aim was to estimate their impact on stroke by gender through population-attributable fraction (PAF), preventive fraction (PF) and their combination in EPIC-Italian cohort. Methods 43,976 participants, age 34–75, and free of cardiovascular disease at baseline (1993–1998) were followed up for almost 11 years. Adjusted hazard ratios and PAF were estimated using Cox models. Results We identified 386 cases. In males, the burden for stroke was 17% (95% CI 4–28%) for smoking and 14% (95% CI 5–22%) for alcohol consumption. In females, hypertension was carrying the biggest burden with 18% (95% CI 9–26%) followed by smoking 15% (95% CI 7–22%). Their combination was 46% (95% CI 32–58%) in males and 48% (95% CI 35–59%) in females. PF for current smokers was gender unequal [males 21% (95% CI 15–27%) females 9% (95% CI 1–17%)]. Conclusions Half of strokes are attributable to potentially modifiable factors. The proportion of prevented cases is gender unbalanced, encouraging sex-specific intervention.

Suggested Citation

  • Slavica Trajkova & Angelo d’Errico & Fulvio Ricceri & Francesca Fasanelli & Valeria Pala & Claudia Agnoli & Rosario Tumino & Graziella Frasca & Giovanna Masala & Calogero Saieva & Paolo Chiodini & Ama, 2017. "Impact of preventable risk factors on stroke in the EPICOR study: does gender matter?," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 62(7), pages 775-786, September.
  • Handle: RePEc:spr:ijphth:v:62:y:2017:i:7:d:10.1007_s00038-017-0993-2
    DOI: 10.1007/s00038-017-0993-2
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s00038-017-0993-2
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1007/s00038-017-0993-2?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Roger B. Newson, 2013. "Attributable and unattributable risks and fractions and other scenario comparisons," Stata Journal, StataCorp LP, vol. 13(4), pages 672-698, December.
    2. Roger Newson, 2012. "Scenario comparisons: How much good can we do?," United Kingdom Stata Users' Group Meetings 2012 01, Stata Users Group.
    3. Mostofsky, E. & Mukamal, K.J. & Giovannucci, E.L. & Stampfer, M.J. & Rimm, E.B., 2016. "Key findings on alcohol consumption and a variety of health outcomes from the nurses' health study," American Journal of Public Health, American Public Health Association, vol. 106(9), pages 1586-1591.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Carolin Malsch & Thomas Liman & Silke Wiedmann & Bob Siegerink & Marios K Georgakis & Steffen Tiedt & Matthias Endres & Peter U Heuschmann, 2018. "Outcome after stroke attributable to baseline factors—The PROSpective Cohort with Incident Stroke (PROSCIS)," PLOS ONE, Public Library of Science, vol. 13(9), pages 1-14, September.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Corsi, Daniel J. & Mejía-Guevara, Iván & Subramanian, S.V., 2016. "Risk factors for chronic undernutrition among children in India: Estimating relative importance, population attributable risk and fractions," Social Science & Medicine, Elsevier, vol. 157(C), pages 165-185.
    2. Brännström, Lars & Karlsson, Henrik & Vinnerljung, Bo & Hjern, Anders, 2018. "Childhood risk factors for disability pension among adult former Swedish child welfare clients: Same or different as for majority population peers?," Children and Youth Services Review, Elsevier, vol. 84(C), pages 94-102.
    3. Doidge, James C & Higgins, Daryl J & Delfabbro, Paul & Edwards, Ben & Vassallo, Suzanne & Toumbourou, John W & Segal, Leonie, 2017. "Economic predictors of child maltreatment in an Australian population-based birth cohort," Children and Youth Services Review, Elsevier, vol. 72(C), pages 14-25.
    4. Brännström, Lars & Vinnerljung, Bo & Hjern, Anders, 2015. "Risk factors for teenage childbirths among child welfare clients: Findings from Sweden," Children and Youth Services Review, Elsevier, vol. 53(C), pages 44-51.
    5. Elaine Tod & Gerry McCartney & Colin Fischbacher & Diane Stockton & James Lewsey & Ian Grant & Grant M A Wyper & Oscar Mesalles-Naranjo & Mag McFadden & Richard Dobbie, 2019. "What causes the burden of stroke in Scotland? A comparative risk assessment approach linking the Scottish Health Survey to administrative health data," PLOS ONE, Public Library of Science, vol. 14(7), pages 1-20, July.
    6. Peter W Young & Andrea A Kim & Joyce Wamicwe & Lilly Nyagah & Catherine Kiama & John Stover & Johansen Oduor & Emily A Rogena & Edwin Walong & Emily Zielinski-Gutierrez & Andrew Imbwaga & Martin Siren, 2017. "HIV-associated mortality in the era of antiretroviral therapy scale-up – Nairobi, Kenya, 2015," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-10, August.
    7. Phuong H Nguyen & Sunny S Kim & Tuan T Nguyen & Lan M Tran & Nemat Hajeebhoy & Edward A Frongillo & Marie T Ruel & Rahul Rawat & Purnima Menon, 2016. "Supply- and Demand-Side Factors Influencing Utilization of Infant and Young Child Feeding Counselling Services in Viet Nam," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-17, March.
    8. Orratai Waleewong & Khanuengnij Yueayai, 2022. "Patterns of Socioeconomic Inequities in SDGs Relating to Children’s Well-Being in Thailand and Policy Implications," IJERPH, MDPI, vol. 19(20), pages 1-15, October.
    9. Alice M Dalton & Andrew P Jones, 2020. "Residential neighbourhood greenspace is associated with reduced risk of cardiovascular disease: A prospective cohort study," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-16, January.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:ijphth:v:62:y:2017:i:7:d:10.1007_s00038-017-0993-2. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.