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The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature

Author

Listed:
  • Anees ur Rehman

    (University Sains Malaysia
    Bahauddin Zakariya University Multan)

  • Mohamed Azmi Ahmad Hassali

    (University Sains Malaysia)

  • Sohail Ayaz Muhammad

    (University Sains Malaysia)

  • Sabariah Noor Harun

    (University Sains Malaysia)

  • Shahid Shah

    (Government College University)

  • Sameen Abbas

    (Quaid e Azam University Islamabad)

Abstract

Objectives To find the economic burden of COPD and to identify the key cost drivers in the management of COPD patients across different European countries. Background COPD is a major cause of mortality and morbidity and is associated with considerable economic burden on the individual and society. It limits the daily activities and working ability of the patients. Methodology We conducted a systematic search of PUBMED, SCIENCE DIRECT, Cochrane CENTRAL, SCOPUS, Google Scholar and SAGE Premier Databases to find scientific research articles evaluating the cost of COPD management from patient and societal perspective. Results Estimated per patient per year direct cost in Norway, Denmark, Germany, Italy, Sweden, Greece, Belgium, and Serbia was €10,701, €9580, €7847, €7448, €7045, €2896, €1963, and €2047, respectively. Annual per patient cost of work productivity loss was highest in Germany as €5735 and lowest in Greece as €998. It was estimated as €4824, €2033 and €1298 in Bulgaria, Denmark and Sweden, respectively. Several factors found associated with increasing cost of COPD management that include but not limited to late diagnosis, severity of disease, frequency of exacerbation, hospital readmissions, non-adherence to the therapy and exposure to COPD risk factors. Conclusion Minimizing the COPD exacerbations and controlling the worsening of symptoms may potentially reduce the cost of COPD management at any stage.

Suggested Citation

  • Anees ur Rehman & Mohamed Azmi Ahmad Hassali & Sohail Ayaz Muhammad & Sabariah Noor Harun & Shahid Shah & Sameen Abbas, 2020. "The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 21(2), pages 181-194, March.
  • Handle: RePEc:spr:eujhec:v:21:y:2020:i:2:d:10.1007_s10198-019-01119-1
    DOI: 10.1007/s10198-019-01119-1
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    References listed on IDEAS

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    1. Jason Foo & Sarah H Landis & Joe Maskell & Yeon-Mok Oh & Thys van der Molen & MeiLan K Han & David M Mannino & Masakazu Ichinose & Yogesh Punekar, 2016. "Continuing to Confront COPD International Patient Survey: Economic Impact of COPD in 12 Countries," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-15, April.
    2. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
    3. Allison Larg & John Moss, 2011. "Cost-of-Illness Studies," PharmacoEconomics, Springer, vol. 29(8), pages 653-671, August.
    4. Kunal Srivastava & Deepika Thakur & Sheetal Sharma & Yogesh Punekar, 2015. "Systematic Review of Humanistic and Economic Burden of Symptomatic Chronic Obstructive Pulmonary Disease," PharmacoEconomics, Springer, vol. 33(5), pages 467-488, May.
    5. Francesco Blasi & Giancarlo Cesana & Sara Conti & Virginio Chiodini & Stefano Aliberti & Carla Fornari & Lorenzo Giovanni Mantovani, 2014. "The Clinical and Economic Impact of Exacerbations of Chronic Obstructive Pulmonary Disease: A Cohort of Hospitalized Patients," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-8, June.
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    Cited by:

    1. Celia Gutiérrez Villegas & María Paz-Zulueta & Manuel Herrero-Montes & Paula Parás-Bravo & María Madrazo Pérez, 2021. "Cost analysis of chronic obstructive pulmonary disease (COPD): a systematic review," Health Economics Review, Springer, vol. 11(1), pages 1-12, December.
    2. Anoma Santiworakul & Nitita Piya-amornphan & Netchanok Jianramas, 2021. "A Home-Based Multimedia Pulmonary Rehabilitation Program Improves Clinical Symptoms and Physical Performance of Patients with Chronic Obstructive Pulmonary Disease," IJERPH, MDPI, vol. 18(21), pages 1-11, October.

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    More about this item

    Keywords

    COPD; Pharmacoeconomics; Direct and indirect cost; Economic burden; Europe; Systematic review;
    All these keywords.

    JEL classification:

    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • H51 - Public Economics - - National Government Expenditures and Related Policies - - - Government Expenditures and Health

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