IDEAS home Printed from https://ideas.repec.org/a/sae/socpsy/v66y2020i7p633-641.html
   My bibliography  Save this article

Very long-term outcome of psychotic disorders

Author

Listed:
  • Vaios Peritogiannis
  • Afroditi Gogou
  • Maria Samakouri

Abstract

Background: The outcome of schizophrenia and related psychoses is generally modest, and patients display high rates of disability. Aims: The aim of the review is to present an up-to-date account of the research on the very long-term outcome of psychotic disorders. Method: We conducted a search in the PubMed and Scopus databases for articles published since the publication of the very long-term data of the World Health Organization’s International Study of Schizophrenia (the ISoS study), over the last 18 years (from 2002 to 2019). Studies were included if they reported on at least 15-year outcome and if they had used valid and reliable tools for the estimation of the patients’ outcome in terms of symptomatology and functioning. Results: A total of 16 studies were included in this review, involving 1,391 patients with schizophrenia and related psychoses. Most were single-center studies, with moderate size samples of patients, and 11 were prospective studies. Very long-term outcome of psychotic disorders varies considerably among studies. Good outcome ranges from 8% to 73.8%, and it appears to be better in developing countries, whereas differences are less apparent among Western countries (8%–40.3%). Studies in different settings have used different methods involving a variety of samples of patients to estimate their outcome, whereas definitions of good and poor outcome also varied among studies. Longer duration of untreated psychosis was associated with worse outcome in some studies. Schizophrenia was found to have poorer long-term prognosis compared to other schizophrenia spectrum disorders. A large proportion of patients, ranging from 19% to 48.2%, were not on medication. Conclusion: Recent evidence on the very long-term outcome of psychotic disorders is in line with previous reports and suggests that prognosis remains rather modest. There are several limitations of current research regarding outcome definitions and study design that should be addressed by future research.

Suggested Citation

  • Vaios Peritogiannis & Afroditi Gogou & Maria Samakouri, 2020. "Very long-term outcome of psychotic disorders," International Journal of Social Psychiatry, , vol. 66(7), pages 633-641, November.
  • Handle: RePEc:sae:socpsy:v:66:y:2020:i:7:p:633-641
    DOI: 10.1177/0020764020922276
    as

    Download full text from publisher

    File URL: https://journals.sagepub.com/doi/10.1177/0020764020922276
    Download Restriction: no

    File URL: https://libkey.io/10.1177/0020764020922276?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Omokehinde O Fakorede & Adegboyega Ogunwale & Akinwande O Akinhanmi, 2020. "Disability among patients with schizophrenia: A hospital-based study," International Journal of Social Psychiatry, , vol. 66(2), pages 179-187, March.
    2. Vaios Peritogiannis & Panagiota Nikolaou, 2020. "Functioning in community-dwelling patients with schizophrenia spectrum disorders in rural Greece," International Journal of Social Psychiatry, , vol. 66(2), pages 111-117, March.
    3. Subhashini Gopal & Greeshma Mohan & Sujit John & Vijaya Raghavan, 2020. "What constitutes recovery in schizophrenia? Client and caregiver perspectives from South India," International Journal of Social Psychiatry, , vol. 66(2), pages 118-123, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Vaios Peritogiannis & Maria Samakouri, 2021. "Research on psychotic disorders in rural areas: Recent advances and ongoing challenges," International Journal of Social Psychiatry, , vol. 67(8), pages 1046-1057, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Vaios Peritogiannis & Sofia Rousoudi & Theofanis Vorvolakos & Panagiota Gioti & Afroditi Gogou & Argiri Arre & Maria Samakouri, 2022. "A comparative study of two Mobile Mental Health Units in different catchment rural areas in Greece," International Journal of Social Psychiatry, , vol. 68(2), pages 324-333, March.
    2. Jonathan Han Loong Kuek & Toby Raeburn & Melissa Yan Zhi Chow & Timothy Wand, 2023. "Lived experiences of mental health conditions in Singapore: A constructivist grounded theory study," International Journal of Social Psychiatry, , vol. 69(3), pages 735-743, May.
    3. Vaios Peritogiannis & Panagiota Gioti & Afroditi Gogou & Maria Samakouri, 2020. "Decrease of hospitalizations and length of hospital stay in patients with schizophrenia spectrum disorders treated in a community mental health service in rural Greece," International Journal of Social Psychiatry, , vol. 66(7), pages 693-699, November.
    4. Shari Tess Mathew & Bergai Parthsarathy Nirmala & John Vijay Sagar Kommu, 2023. "Personal meaning of recovery among persons with schizophrenia," International Journal of Social Psychiatry, , vol. 69(1), pages 78-85, February.
    5. Vaios Peritogiannis & Ioannis Drakatos & Panagiota Gioti & Aikaterini Garbi, 2023. "Vaccination rates against COVID-19 in patients with severe mental illness attending community mental health services in rural Greece," International Journal of Social Psychiatry, , vol. 69(1), pages 208-215, February.
    6. Vaios Peritogiannis & Maria Samakouri, 2021. "Research on psychotic disorders in rural areas: Recent advances and ongoing challenges," International Journal of Social Psychiatry, , vol. 67(8), pages 1046-1057, December.
    7. Manuel Rojas & Maite Barrios & Juana Gómez-Benito & Nadezhda Mikheenkova & Sergey Mosolov, 2021. "Functioning Problems in Persons with Schizophrenia in the Russian Context," IJERPH, MDPI, vol. 18(19), pages 1-14, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:sae:socpsy:v:66:y:2020:i:7:p:633-641. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: SAGE Publications (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.