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Impact on Decisions to Start or Continue Medicines of Providing Information to Patients about Possible Benefits and/or Harms

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  • Rachel A. Crockett
  • Stephen Sutton
  • Fiona M. Walter
  • Megan Clinch
  • Theresa M. Marteau
  • John Benson

Abstract

Background . The impact of providing information about medicines to patients on decisions about starting or continuing them is unknown. Purpose . To estimate the impact on decisions to start or continue medicines, of providing information to patients about possible benefits and/or harms. Data Sources . Electronic searches from 1980 to October 2010; reference and citation searches of included studies. Study Selection . Two investigators assessed studies' eligibility against inclusion criteria: randomized or pseudorandomized trials; participants older than 16 years and deciding for themselves; one group received information about possible benefits and/or harms of a potentially beneficial medicine, compared with another who did not; d) a measure of decision about starting or continuing a medicine. Data Extraction . One investigator extracted all data, checked by a second. Data Synthesis . Eight studies were included, covering a range of medicines. There was no consistent impact of interventions on decisions about whether to start or continue medicines (pooled odds ratio 1.08; 95% confidence interval [CI], 0.69–1.70; P = 0.74 ). Among those who received more information, knowledge was increased (pooled mean difference 8.47; 95% CI 2.17–14.77; P = 0.008), and decisional conflict was reduced (pooled mean difference -0.15; 95% CI -0.24 to -0.06; P = .001). Limitations . A small number of studies across different clinical contexts, of uncertain heterogeneity, were included. Conclusions . Providing information to patients about possible benefits and/or harms has no consistent effect on the number who decide to start or continue medicines, although it increases patients' knowledge and reduces their decisional conflict.

Suggested Citation

  • Rachel A. Crockett & Stephen Sutton & Fiona M. Walter & Megan Clinch & Theresa M. Marteau & John Benson, 2011. "Impact on Decisions to Start or Continue Medicines of Providing Information to Patients about Possible Benefits and/or Harms," Medical Decision Making, , vol. 31(5), pages 767-777, September.
    • Handle: RePEc:sae:medema:v:31:y:2011:i:5:p:767-777
    DOI: 10.1177/0272989X11400420
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    References listed on IDEAS

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    1. Charles, Cathy & Gafni, Amiram & Whelan, Tim, 1997. "Shared decision-making in the medical encounter: What does it mean? (or it takes at least two to tango)," Social Science & Medicine, Elsevier, vol. 44(5), pages 681-692, March.
    2. Pound, Pandora & Britten, Nicky & Morgan, Myfanwy & Yardley, Lucy & Pope, Catherine & Daker-White, Gavin & Campbell, Rona, 2005. "Resisting medicines: a synthesis of qualitative studies of medicine taking," Social Science & Medicine, Elsevier, vol. 61(1), pages 133-155, July.
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