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The local stability of a modified multi-strain SIR model for emerging viral strains

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  • Miguel Fudolig
  • Reka Howard

Abstract

We study a novel multi-strain SIR epidemic model with selective immunity by vaccination. A newer strain is made to emerge in the population when a preexisting strain has reached equilbrium. We assume that this newer strain does not exhibit cross-immunity with the original strain, hence those who are vaccinated and recovered from the original strain become susceptible to the newer strain. Recent events involving the COVID-19 virus shows that it is possible for a viral strain to emerge from a population at a time when the influenza virus, a well-known virus with a vaccine readily available, is active in a population. We solved for four different equilibrium points and investigated the conditions for existence and local stability. The reproduction number was also determined for the epidemiological model and found to be consistent with the local stability condition for the disease-free equilibrium.

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  • Miguel Fudolig & Reka Howard, 2020. "The local stability of a modified multi-strain SIR model for emerging viral strains," PLOS ONE, Public Library of Science, vol. 15(12), pages 1-27, December.
    • Handle: RePEc:plo:pone00:0243408
    DOI: 10.1371/journal.pone.0243408
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    Cited by:

    1. Wu, Yucui & Zhang, Zhipeng & Song, Limei & Xia, Chengyi, 2024. "Global stability analysis of two strains epidemic model with imperfect vaccination and immunity waning in a complex network," Chaos, Solitons & Fractals, Elsevier, vol. 179(C).

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