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Full-dose hepatitis B virus vaccination coverage and associated factors among health care workers in Ethiopia: A systematic review and meta-analysis

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Listed:
  • Nefsu Awoke
  • Henok Mulgeta
  • Tsegaye Lolaso
  • Tiwabwork Tekalign
  • Serawit Samuel
  • Mohammed Suleiman Obsa
  • Robera Olana

Abstract

Introduction: The hepatitis B vaccine is the backbone of hepatitis B prevention. All health care workers must receive a full-dose (3-dose vaccine series) to achieve >90% protection against hepatitis B virus. There is limited evidence available on vaccination coverage of HBV among health care workers in Ethiopia. Therefore, the objective of this study was to estimate the national full-dose hepatitis B vaccination coverage and the associated factors among health care workers in Ethiopia. Methods: Studies were retrieved from PubMed, EMBASE, Web of Science, SCOPUS, CINAHL, and Google Scholar by using a combination of search terms with Boolean operators. The quality of each study was evaluated independently by three authors using the modified Newcastle-Ottawa Scale (NOS) for cross-sectional studies. Statistical analyses were performed using STATA™ Version 14 software. Meta-analysis was carried out using a random-effects (DerSimonian and Laird) method. The heterogeneity test was conducted by using I-squared (I2) statistics. Leave-one-out sensitivity analysis was performed. Results: A total of 15 articles with 5734 participants were included in this systematic review and meta-analysis. The pooled prevalence of full-dose hepatitis B virus vaccination coverage among health care workers in Ethiopia was 20.04% (95% CI: 13.83, 26.26); I2 = 98.9%). Being male sex (p = 0.002), having work experience of less than 5 years (p

Suggested Citation

  • Nefsu Awoke & Henok Mulgeta & Tsegaye Lolaso & Tiwabwork Tekalign & Serawit Samuel & Mohammed Suleiman Obsa & Robera Olana, 2020. "Full-dose hepatitis B virus vaccination coverage and associated factors among health care workers in Ethiopia: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-15, October.
    • Handle: RePEc:plo:pone00:0241226
    DOI: 10.1371/journal.pone.0241226
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