Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis
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DOI: 10.1371/journal.pone.0241122
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- Kazuhiko Yamane & Irene L Indalao & Junji Chida & Yoshikazu Yamamoto & Masaaki Hanawa & Hiroshi Kido, 2014. "Diisopropylamine Dichloroacetate, a Novel Pyruvate Dehydrogenase Kinase 4 Inhibitor, as a Potential Therapeutic Agent for Metabolic Disorders and Multiorgan Failure in Severe Influenza," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-13, May.
- Oscar R. Colegio & Ngoc-Quynh Chu & Alison L. Szabo & Thach Chu & Anne Marie Rhebergen & Vikram Jairam & Nika Cyrus & Carolyn E. Brokowski & Stephanie C. Eisenbarth & Gillian M. Phillips & Gary W. Cli, 2014. "Functional polarization of tumour-associated macrophages by tumour-derived lactic acid," Nature, Nature, vol. 513(7519), pages 559-563, September.
- Liangchun Yang & Min Xie & Minghua Yang & Yan Yu & Shan Zhu & Wen Hou & Rui Kang & Michael T. Lotze & Timothy R. Billiar & Haichao Wang & Lizhi Cao & Daolin Tang, 2014. "PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis," Nature Communications, Nature, vol. 5(1), pages 1-9, December.
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