IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0230338.html
   My bibliography  Save this article

Immunochromatography for the diagnosis of Mycoplasma pneumoniae infection: A systematic review and meta-analysis

Author

Listed:
  • Seo Hee Yoon
  • In Kyung Min
  • Jong Gyun Ahn

Abstract

The aim of this study was to evaluate the diagnostic performance of immunochromatographic tests (ICTs) for the detection of Mycoplasma pneumoniae. Medline/Pubmed, Embase, the Cochrane Library, and ISI Web of Science were searched through June 12, 2019 for relevant studies that used ICTs for the detection of M. pneumoniae infection with polymerase chain reaction (PCR) or microbial culturing as reference standards. Pooled diagnostic accuracy with 95% confidence interval (CI) was calculated using a bivariate random effects model. We also constructed summary receiver operating characteristic curves and calculated the area under the curve (AUC). Statistical heterogeneity was evaluated by χ2 test or Cochrane’s Q test. Thirteen studies including 2,235 samples were included in the meta-analysis. The pooled sensitivity and specificity for diagnosing M. pneumoniae infection were 0.70 (95% CI: 0.59–0.79) and 0.92 (95% CI: 0.87–0.95), respectively. The positive likelihood ratio (LR) was 8.94 (95% CI: 4.90–14.80), negative LR 0.33 (95% CI: 0.22–0.46), diagnostic odds ratio 29.20 (95% CI: 10.70–64.20), and AUC 0.904. In subgroup analysis, ICTs demonstrated similar pooled sensitivities and specificities in populations of children only and mixed populations (children + adults). Specimens obtained from oropharyngeal swabs exhibited a higher sensitivity and specificity than those of nasopharyngeal swab. Moreover, pooled estimates of sensitivity and accuracy for studies using PCR as a reference standard were higher than those using culture. The pooled sensitivity and specificity of Ribotest Mycoplasma®, the commercial kit most commonly used in the included studies, were 0.66 and 0.89, respectively. Overall, ICT is a rapid user-friendly method for diagnosing M. pneumoniae infection with moderate sensitivity, high specificity, and high accuracy. This suggests that ICT may be useful in the diagnostic workup of M. pneumoniae infection; however, additional studies are needed for evaluating the potential impact of ICT in clinical practice.

Suggested Citation

  • Seo Hee Yoon & In Kyung Min & Jong Gyun Ahn, 2020. "Immunochromatography for the diagnosis of Mycoplasma pneumoniae infection: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(3), pages 1-17, March.
    • Handle: RePEc:plo:pone00:0230338
    DOI: 10.1371/journal.pone.0230338
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230338
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0230338&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0230338?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Unknown, 2004. "Table of Contents," International Food and Agribusiness Management Review, International Food and Agribusiness Management Association, vol. 7(4), pages 1-1.
    2. Unknown, 2004. "Table of Contents," International Food and Agribusiness Management Review, International Food and Agribusiness Management Association, vol. 7(2), pages 1-1.
    3. Unknown, 2004. "Table of Contents," International Food and Agribusiness Management Review, International Food and Agribusiness Management Association, vol. 7(3), pages 1-1.
    4. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    5. Unknown, 2004. "Table of Contents," International Food and Agribusiness Management Review, International Food and Agribusiness Management Association, vol. 7(1), pages 1-1.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Daisuke Nakajima & Hiromasa Kawakami & Takahiro Mihara & Hitoshi Sato & Takahisa Goto, 2020. "Effectiveness of intravenous lidocaine in preventing postoperative nausea and vomiting in pediatric patients: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-13, January.
    2. Jian Zhang & Xuena Zhang & Hui Wang & Haibin Zhou & Tian Tian & Anshi Wu, 2017. "Dexmedetomidine as a neuraxial adjuvant for prevention of perioperative shivering: Meta-analysis of randomized controlled trials," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-17, August.
    3. Elisa Sicuri & Azucena Bardají & Betuel Sigauque & Maria Maixenchs & Ariel Nhacolo & Delino Nhalungo & Eusebio Macete & Pedro L Alonso & Clara Menéndez, 2011. "Costs Associated with Low Birth Weight in a Rural Area of Southern Mozambique," PLOS ONE, Public Library of Science, vol. 6(12), pages 1-9, December.
    4. Shan Luo & Zehua Chen, 2014. "Sequential Lasso Cum EBIC for Feature Selection With Ultra-High Dimensional Feature Space," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 109(507), pages 1229-1240, September.
    5. Xuling Liu & Yang Yu & Shengmei Zhu, 2018. "Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies," PLOS ONE, Public Library of Science, vol. 13(4), pages 1-22, April.
    6. Michelle Giles & Laura Graham & Jean Ball & Jennie King & Wendy Watts & Alison Harris & Christopher Oldmeadow & Rod Ling & Michelle Paul & Anthony O’Brien & Vicki Parker & John Wiggers & Maralyn Foure, 2020. "Implementation of a multifaceted nurse‐led intervention to reduce indwelling urinary catheter use in four Australian hospitals: A pre‐ and postintervention study," Journal of Clinical Nursing, John Wiley & Sons, vol. 29(5-6), pages 872-886, March.
    7. Qi-ling Yuan & Tuan-mao Guo & Liang Liu & Fu Sun & Yin-gang Zhang, 2015. "Traditional Chinese Medicine for Neck Pain and Low Back Pain: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(2), pages 1-37, February.
    8. Cheemeng Tan & Robert Phillip Smith & Ming-Chi Tsai & Russell Schwartz & Lingchong You, 2014. "Phenotypic Signatures Arising from Unbalanced Bacterial Growth," PLOS Computational Biology, Public Library of Science, vol. 10(8), pages 1-10, August.
    9. Anura Amarasinghe & Gerard D'Souza & Cheryl Brown & Hyungna Oh, 2006. "The Influence of Socioeconomic and Environmental Factors on Health and Obesity in Rural Appalachia," Working Papers Working Paper 2006-12, Regional Research Institute, West Virginia University.
    10. Michelle Tew & Philip Clarke & Karin Thursky & Kim Dalziel, 2019. "Incorporating Future Medical Costs: Impact on Cost-Effectiveness Analysis in Cancer Patients," PharmacoEconomics, Springer, vol. 37(7), pages 931-941, July.
    11. Meghan A Kirksey & Stephen C Haskins & Jennifer Cheng & Spencer S Liu, 2015. "Local Anesthetic Peripheral Nerve Block Adjuvants for Prolongation of Analgesia: A Systematic Qualitative Review," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-23, September.
    12. Su Han & Xiaoli Zhang & Jingshan Wen & Yihong Li & Jing Shu & Hong Ling & Fengmin Zhang, 2012. "A Combination of the Kato-Katz Methods and ELISA to Improve the Diagnosis of Clonorchiasis in an Endemic Area, China," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-8, October.
    13. Frederick Schneider & Jan Martin & Alexander Hapfelmeier & Denis Jordan & Gerhard Schneider & Christian M Schulz, 2017. "The validity of linear and non-linear heart rate metrics as workload indicators of emergency physicians," PLOS ONE, Public Library of Science, vol. 12(11), pages 1-12, November.
    14. Jun’ichi Kotoku & Asuka Oyama & Kanako Kitazumi & Hiroshi Toki & Akihiro Haga & Ryohei Yamamoto & Maki Shinzawa & Miyae Yamakawa & Sakiko Fukui & Keiichi Yamamoto & Toshiki Moriyama, 2020. "Causal relations of health indices inferred statistically using the DirectLiNGAM algorithm from big data of Osaka prefecture health checkups," PLOS ONE, Public Library of Science, vol. 15(12), pages 1-19, December.
    15. Juan Ni & Jiafu Wei & Yusheng Yao & Xiaoqin Jiang & Linli Luo & Dong Luo, 2015. "Effect of Dexmedetomidine on Preventing Postoperative Agitation in Children: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-13, May.
    16. Amarzaya Jadambaa & Nicholas Graves & Donna Cross & Rosana Pacella & Hannah J. Thomas & James G. Scott & Qinglu Cheng & David Brain, 2022. "Economic Evaluation of an Intervention Designed to Reduce Bullying in Australian Schools," Applied Health Economics and Health Policy, Springer, vol. 20(1), pages 79-89, January.
    17. Åsa Wallström & Gunilla Hollman Frisman, 2014. "Facilitating early recovery of bowel motility after colorectal surgery: a systematic review," Journal of Clinical Nursing, John Wiley & Sons, vol. 23(1-2), pages 24-44, January.
    18. Hye Won Shin & Bum Jun Ju & Yoo Kyung Jang & Hae Seun You & Hyun Kang & Ji Yong Park, 2017. "Effect of tramadol as an adjuvant to local anesthetics for brachial plexus block: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-19, September.
    19. Jian Yu & Li Ren & Su Min & You Yang & Feng Lv, 2020. "Nebulized pharmacological agents for preventing postoperative sore throat: A systematic review and network meta-analysis," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-14, August.
    20. repec:rri:wpaper:200612 is not listed on IDEAS
    21. Michelle Giles & Laura Graham & Jean Ball & Wendy Watts & Jennie King & Kamana Bantawa & Michelle Paul & Alison Harris & Anthony Paul O'Brien & Vicki Parker, 2019. "Variations in indwelling urinary catheter use in four Australian acute care hospitals," Journal of Clinical Nursing, John Wiley & Sons, vol. 28(23-24), pages 4572-4581, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0230338. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.