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The Efficacy of a Nurse-Led Disease Management Program in Improving the Quality of Life for Patients with Chronic Kidney Disease: A Meta-Analysis

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Listed:
  • Chong-Cheng Chen
  • Yi Chen
  • Xia Liu
  • Yue Wen
  • Deng-Yan Ma
  • Yue-Yang Huang
  • Li Pu
  • Yong-Shu Diao
  • Kun Yang

Abstract

Background: The impacts of nurse-led disease management programs on the quality of life for patients with chronic kidney disease have not been extensively studied. Furthermore, results of the existing related studies are inconsistent. The focus of the proposed meta-analysis is to evaluate the efficacy of nurse-led disease management programs in improving the quality of life for patients with chronic kidney disease. Methods: Literature survey was performed to identify the eligible studies from PubMed, Current Nursing and Allied Health Literature, and Cochrane Central Register of Controlled Trials with predefined terms. The outcome measured was quality of life. This meta-analysis was conducted in line with recommendations from the preferred reporting items for systematic reviews and meta-analyses. Results: Eight studies comprising a total of 1520 patients were included in this meta-analysis, with 766 patients assigned to the nurse-led disease management program. Nurse-led disease management improved the quality of life in terms of symptoms, sleep, staff encouragement, pain, general health perception, energy/fatigue, overall health and mental component summary when evaluated 6 weeks after the beginning of intervention. When evaluated 12 weeks later, the quality of life in terms of symptoms, sleep, staff encouragement, energy/fatigue, and physical component summary was improved. Stratified by the modalities of dialysis, similar results of pooled analyses were observed for patients with peritoneal dialysis or hemodialysis, compared with the overall analyses. The results of sensitivity analyses were the same as the primary analyses. The symmetric funnel plot suggested that the possibility of potential publication bias was relatively low. Conclusion: Nurse-led disease management program seems effective to improve some parameters of quality of life for patients with chronic kidney disease. However, the seemingly promising results should be cautiously interpreted and generalized and still need to be confirmed through well-designed large-scale prospective randomized controlled trials.

Suggested Citation

  • Chong-Cheng Chen & Yi Chen & Xia Liu & Yue Wen & Deng-Yan Ma & Yue-Yang Huang & Li Pu & Yong-Shu Diao & Kun Yang, 2016. "The Efficacy of a Nurse-Led Disease Management Program in Improving the Quality of Life for Patients with Chronic Kidney Disease: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(5), pages 1-16, May.
    • Handle: RePEc:plo:pone00:0155890
    DOI: 10.1371/journal.pone.0155890
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    1. Kun Yang & Hai-Ning Chen & Xin-Zu Chen & Qing-Chun Lu & Lin Pan & Jie Liu & Bin Dai & Bo Zhang & Zhi-Xin Chen & Jia-Ping Chen & Jian-Kun Hu, 2012. "Transthoracic Resection versus Non-Transthoracic Resection for Gastroesophageal Junction Cancer: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(6), pages 1-13, June.
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    Cited by:

    1. Marques Shek Nam Ng & Cho Lee Wong & Eva Hau Sim Ho & Yun Ho Hui & Christine Miaskowski & Winnie Kwok Wei So, 2020. "Burden of living with multiple concurrent symptoms in patients with end‐stage renal disease," Journal of Clinical Nursing, John Wiley & Sons, vol. 29(13-14), pages 2589-2601, July.

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