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Physiologic Status Monitoring via the Gastrointestinal Tract

Author

Listed:
  • G Traverso
  • G Ciccarelli
  • S Schwartz
  • T Hughes
  • T Boettcher
  • R Barman
  • R Langer
  • A Swiston

Abstract

Reliable, real-time heart and respiratory rates are key vital signs used in evaluating the physiological status in many clinical and non-clinical settings. Measuring these vital signs generally requires superficial attachment of physically or logistically obtrusive sensors to subjects that may result in skin irritation or adversely influence subject performance. Given the broad acceptance of ingestible electronics, we developed an approach that enables vital sign monitoring internally from the gastrointestinal tract. Here we report initial proof-of-concept large animal (porcine) experiments and a robust processing algorithm that demonstrates the feasibility of this approach. Implementing vital sign monitoring as a stand-alone technology or in conjunction with other ingestible devices has the capacity to significantly aid telemedicine, optimize performance monitoring of athletes, military service members, and first-responders, as well as provide a facile method for rapid clinical evaluation and triage.

Suggested Citation

  • G Traverso & G Ciccarelli & S Schwartz & T Hughes & T Boettcher & R Barman & R Langer & A Swiston, 2015. "Physiologic Status Monitoring via the Gastrointestinal Tract," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-13, November.
    • Handle: RePEc:plo:pone00:0141666
    DOI: 10.1371/journal.pone.0141666
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    Cited by:

    1. Ernesto De la Paz & Nikhil Harsha Maganti & Alexander Trifonov & Itthipon Jeerapan & Kuldeep Mahato & Lu Yin & Thitaporn Sonsa-ard & Nicolas Ma & Won Jung & Ryan Burns & Amir Zarrinpar & Joseph Wang &, 2022. "A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites," Nature Communications, Nature, vol. 13(1), pages 1-11, December.

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