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HemI: A Toolkit for Illustrating Heatmaps

Author

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  • Wankun Deng
  • Yongbo Wang
  • Zexian Liu
  • Han Cheng
  • Yu Xue

Abstract

Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-to-use tool named HemI (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, HemI provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that HemI can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of HemI were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php.

Suggested Citation

  • Wankun Deng & Yongbo Wang & Zexian Liu & Han Cheng & Yu Xue, 2014. "HemI: A Toolkit for Illustrating Heatmaps," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-5, November.
    • Handle: RePEc:plo:pone00:0111988
    DOI: 10.1371/journal.pone.0111988
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    1. Tieshuai Du & Zebin Lin & Yaling Xie & Xing Ye & Chunyan Tu & Kaidi Jin & Jianhui Xie & Yiwen Shen, 2018. "Metabolic profiling of femoral muscle from rats at different periods of time after death," PLOS ONE, Public Library of Science, vol. 13(9), pages 1-15, September.
    2. Huilan Zhang & Piaopiao Liang & Ying Liu & Xinglei Wang & Yahong Bai & Yunxin Xing & Chunli Wei & Yuanyuan Li & Yiming Liu & Yu Hu, 2022. "Spatial Distributions and Intrinsic Influence Analysis of Cr, Ni, Cu, Zn, As, Cd and Pb in Sediments from the Wuliangsuhai Wetland, China," IJERPH, MDPI, vol. 19(17), pages 1-16, August.
    3. Ya-Ling Yang & Hsiao-Ling Yang & S. Pamela K. Shiao, 2018. "Meta-Prediction of MTHFR Gene Polymorphisms and Air Pollution on the Risk of Hypertensive Disorders in Pregnancy Worldwide," IJERPH, MDPI, vol. 15(2), pages 1-14, February.
    4. Zhao-Jin Chen & Yang Shao & Ying-Jun Li & Li-An Lin & Yan Chen & Wei Tian & Bai-Lian Li & Yu-Ying Li, 2020. "Rhizosphere Bacterial Community Structure and Predicted Functional Analysis in the Water-Level Fluctuation Zone of the Danjiangkou Reservoir in China During the Dry Period," IJERPH, MDPI, vol. 17(4), pages 1-18, February.

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