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HTSstation: A Web Application and Open-Access Libraries for High-Throughput Sequencing Data Analysis

Author

Listed:
  • Fabrice P A David
  • Julien Delafontaine
  • Solenne Carat
  • Frederick J Ross
  • Gregory Lefebvre
  • Yohan Jarosz
  • Lucas Sinclair
  • Daan Noordermeer
  • Jacques Rougemont
  • Marion Leleu

Abstract

The HTSstation analysis portal is a suite of simple web forms coupled to modular analysis pipelines for various applications of High-Throughput Sequencing including ChIP-seq, RNA-seq, 4C-seq and re-sequencing. HTSstation offers biologists the possibility to rapidly investigate their HTS data using an intuitive web application with heuristically pre-defined parameters. A number of open-source software components have been implemented and can be used to build, configure and run HTS analysis pipelines reactively. Besides, our programming framework empowers developers with the possibility to design their own workflows and integrate additional third-party software. The HTSstation web application is accessible at http://htsstation.epfl.ch.

Suggested Citation

  • Fabrice P A David & Julien Delafontaine & Solenne Carat & Frederick J Ross & Gregory Lefebvre & Yohan Jarosz & Lucas Sinclair & Daan Noordermeer & Jacques Rougemont & Marion Leleu, 2014. "HTSstation: A Web Application and Open-Access Libraries for High-Throughput Sequencing Data Analysis," PLOS ONE, Public Library of Science, vol. 9(1), pages 1-9, January.
    • Handle: RePEc:plo:pone00:0085879
    DOI: 10.1371/journal.pone.0085879
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    1. Helen M. Rowe & Johan Jakobsson & Daniel Mesnard & Jacques Rougemont & Séverine Reynard & Tugce Aktas & Pierre V. Maillard & Hillary Layard-Liesching & Sonia Verp & Julien Marquis & François Spitz & D, 2010. "KAP1 controls endogenous retroviruses in embryonic stem cells," Nature, Nature, vol. 463(7278), pages 237-240, January.
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