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Effect of Hydrophobic Acrylic versus Hydrophilic Acrylic Intraocular Lens on Posterior Capsule Opacification: Meta-Analysis

Author

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  • Ying Li
  • Jiaxing Wang
  • Zhuo Chen
  • Xin Tang

Abstract

Purpose: This meta-analysis aims to evaluate the differences in performance of posterior capsular opacification (PCO) between hydrophobic acrylic intraocular lens (IOLs) and hydrophilic acrylic IOLs. Setting: Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin, China. Design: Systematic review of randomized controlled trials (RCTs) or meta-analysis. Methods: An electronic literature search was performed using the PubMed, EMBASE and Cochrane Library database before May in 2013 to identify prospective RCTs comparing hydrophobic acrylic IOLs and hydrophilic acrylic IOLs in patients after phacoemulsification with IOL implantation with a follow-up time of at least 1 year. Pertinent studies were selected by meeting predefined criteria and reviewed systematically by meta-analysis. The PCO scores and YAG capsulotomy rate, as indicator of PCO, were measured and discussed in a meta-analysis. Standardized mean differences (SMD), relative risk ratio (RR), and the pooled estimates were computed according to a random effect model or fixed effect model. Results: Nine prospective RCTs involving 861 eyes were included in the current meta-analysis. The hydrophobic acrylic IOLs were favored and the pooled SMD of PCO severity was1.72 (95% confidence interval (CI), 0.20 to 1.23, P = 0.0002) and 1.79 (95% CI, 0.95 to 2.64, P

Suggested Citation

  • Ying Li & Jiaxing Wang & Zhuo Chen & Xin Tang, 2013. "Effect of Hydrophobic Acrylic versus Hydrophilic Acrylic Intraocular Lens on Posterior Capsule Opacification: Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-7, November.
    • Handle: RePEc:plo:pone00:0077864
    DOI: 10.1371/journal.pone.0077864
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    References listed on IDEAS

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    1. Xiao-feng Zhu & Hai-dong Zou & Yong-fu Yu & Qian Sun & Nai-qing Zhao, 2012. "Comparison of Blue Light-Filtering IOLs and UV Light-Filtering IOLs for Cataract Surgery: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(3), pages 1-10, March.
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    Cited by:

    1. Shuo Zhang & Jiaxing Wang & Ying Li & Ye Liu & Li He & Xiaobo Xia, 2019. "The role of primary intraocular lens implantation in the risk of secondary glaucoma following congenital cataract surgery: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 14(4), pages 1-12, April.
    2. Meng-yao Han & Ai-hua Yu & Jing Yuan & Xiao-jun Cai & Jiang-bo Ren, 2019. "Effect of anterior capsule polish on visual function: A meta-analysis," PLOS ONE, Public Library of Science, vol. 14(1), pages 1-12, January.
    3. Howard Thom & Frank Ender & Saisudha Samavedam & Caridad Perez Vivez & Subhajit Gupta & Mukesh Dhariwal & Jan de Haan & Derek O’Boyle, 2019. "Effect of AcrySof versus other intraocular lens properties on the risk of Nd:YAG capsulotomy after cataract surgery: A systematic literature review and network meta-analysis," PLOS ONE, Public Library of Science, vol. 14(8), pages 1-15, August.

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