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Incidence of Type 2 Diabetes in Japan: A Systematic Review and Meta-Analysis

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  • Atsushi Goto
  • Maki Goto
  • Mitsuhiko Noda
  • Shoichiro Tsugane

Abstract

Background: The definition of incident type 2 diabetes varies across studies; hence, the actual incidence of type 2 diabetes in Japan is unclear. Here, we reviewed the various definitions of incident type 2 diabetes used in previous epidemiologic studies and estimated the diabetes incidence rate in Japan. Methods: We searched for related literature in the MEDLINE, EMBASE, and Ichushi databases through September 2012. Two reviewers selected studies that evaluated incident type 2 diabetes in the Japanese population. Results: From 1824 relevant articles, we included 33 studies with 386,803 participants. The follow-up period ranged from 2.3 to 14 years and the studies were initiated between 1980 and 2003. The random-effects model indicated that the pooled incidence rate of diabetes was 8.8 (95% confidence interval, 7.4–10.4) per 1000 person-years. We observed a high degree of heterogeneity in the results (I2 = 99.2%; p

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  • Atsushi Goto & Maki Goto & Mitsuhiko Noda & Shoichiro Tsugane, 2013. "Incidence of Type 2 Diabetes in Japan: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(9), pages 1-1, September.
    • Handle: RePEc:plo:pone00:0074699
    DOI: 10.1371/journal.pone.0074699
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    1. Roger M. Harbord & Julian P.T. Higgins, 2008. "Meta-regression in Stata," Stata Journal, StataCorp LP, vol. 8(4), pages 493-519, December.
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