IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0071899.html
   My bibliography  Save this article

Cancer Mortality in Chinese Chrysotile Asbestos Miners: Exposure-Response Relationships

Author

Listed:
  • Xiaorong Wang
  • Eiji Yano
  • Sihao Lin
  • Ignatius T S Yu
  • Yajia Lan
  • Lap Ah Tse
  • Hong Qiu
  • David C Christiani

Abstract

Objective: This study was conducted to assess the relationship of mortality from lung cancer and other selected causes to asbestos exposure levels. Methods: A cohort of 1539 male workers from a chrysotile mine in China was followed for 26 years. Data on vital status, occupation and smoking were collected from the mine records and individual contacts. Causes and dates of death were further verified from the local death registry. Individual cumulative fibre exposures (f-yr/ml) were estimated based on converted dust measurements and working years at specific workshops. Standardized mortality ratios (SMRs) for lung cancer, gastrointestinal (GI) cancer, all cancers and nonmalignant respiratory diseases (NMRD) stratified by employment years, estimated cumulative fibre exposures, and smoking, were calculated. Poisson models were fitted to determine exposure-response relationships between estimated fibre exposures and cause-specific mortality, adjusting for age and smoking. Results: SMRs for lung cancer increased with employment years at entry to the study, by 3.5-fold in ≥10 years and 5.3-fold in ≥20 years compared with

Suggested Citation

  • Xiaorong Wang & Eiji Yano & Sihao Lin & Ignatius T S Yu & Yajia Lan & Lap Ah Tse & Hong Qiu & David C Christiani, 2013. "Cancer Mortality in Chinese Chrysotile Asbestos Miners: Exposure-Response Relationships," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-8, August.
  • Handle: RePEc:plo:pone00:0071899
    DOI: 10.1371/journal.pone.0071899
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071899
    Download Restriction: no

    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071899&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pone.0071899?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Stayner, L.T. & Danhovic, D.A. & Lemen, R.A., 1996. "Occupational exposure to chrysotile asbestos and cancer risk: A review of the amphibole hypothesis," American Journal of Public Health, American Public Health Association, vol. 86(2), pages 179-186.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Deiana, Claudio & Giua, Ludovica, 2023. "This site is closed! The effect of decommissioning mining waste facilities on mortality in the long run," Journal of Environmental Economics and Management, Elsevier, vol. 119(C).
    2. Yuwadee Ngamwong & Wimonchat Tangamornsuksan & Ornrat Lohitnavy & Nathorn Chaiyakunapruk & C Norman Scholfield & Brad Reisfeld & Manupat Lohitnavy, 2015. "Additive Synergism between Asbestos and Smoking in Lung Cancer Risk: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(8), pages 1-19, August.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Powell, Mark, 1996. "The 1983-84 Suspensions of EDB Under FIFRA and the 1989 Asbestos Ban and Phaseout Rule Under TSCA: Two Case Studies in EPA's Use of Science," RFF Working Paper Series dp-97-06-rev, Resources for the Future.
    2. Powell, Mark R., 1997. "The 1983-84 Suspensions of EDB under FIFRA and the 1989 Asbestos Ban and Phaseout Rule under TSCA: Two Case Studies in EPA's Use of Science," Discussion Papers 10907, Resources for the Future.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0071899. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.