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Incidence and Risk Factors for Tuberculosis in People Living with HIV: Cohort from HIV Referral Health Centers in Recife, Brazil

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  • Joanna d’Arc Lyra Batista
  • Maria de Fátima Pessoa Militão de Albuquerque
  • Magda Maruza
  • Ricardo Arraes de Alencar Ximenes
  • Marcela Lopes Santos
  • Ulisses Ramos Montarroyos
  • Demócrito de Barros Miranda-Filho
  • Heloisa Ramos Lacerda
  • Laura Cunha Rodrigues

Abstract

Objective: To identify the incidence of and risk factors for tuberculosis in people living with HIV (PLHIV). Design: Observational, prospective cohort study. Methods: A total of 2069 HIV-infected patients was observed between July 2007 and December 2010. The Kaplan-Meier method was used to estimate the probability of survival free of tuberculosis, and Cox regression analysis to identify risk factors associated with the development of tuberculosis. Results: Survival free of tuberculosis (TB) was 91%. The incidence rate of tuberculosis was 2.8 per 100 persons/years. Incidence of tuberculosis was higher when subjects had CD4 cell count

Suggested Citation

  • Joanna d’Arc Lyra Batista & Maria de Fátima Pessoa Militão de Albuquerque & Magda Maruza & Ricardo Arraes de Alencar Ximenes & Marcela Lopes Santos & Ulisses Ramos Montarroyos & Demócrito de Barros Mi, 2013. "Incidence and Risk Factors for Tuberculosis in People Living with HIV: Cohort from HIV Referral Health Centers in Recife, Brazil," PLOS ONE, Public Library of Science, vol. 8(5), pages 1-8, May.
    • Handle: RePEc:plo:pone00:0063916
    DOI: 10.1371/journal.pone.0063916
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    1. Amitabh B Suthar & Stephen D Lawn & Julia del Amo & Haileyesus Getahun & Christopher Dye & Delphine Sculier & Timothy R Sterling & Richard E Chaisson & Brian G Williams & Anthony D Harries & Reuben M , 2012. "Antiretroviral Therapy for Prevention of Tuberculosis in Adults with HIV: A Systematic Review and Meta-Analysis," PLOS Medicine, Public Library of Science, vol. 9(7), pages 1-15, July.
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