IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0037413.html
   My bibliography  Save this article

Conflict of Interest Policies for Organizations Producing a Large Number of Clinical Practice Guidelines

Author

Listed:
  • Susan L Norris
  • Haley K Holmer
  • Brittany U Burda
  • Lauren A Ogden
  • Rongwei Fu

Abstract

Background: Conflict of interest (COI) of clinical practice guideline (CPG) sponsors and authors is an important potential source of bias in CPG development. The objectives of this study were to describe the COI policies for organizations currently producing a significant number of CPGs, and to determine if these policies meet 2011 Institute of Medicine (IOM) standards. Methodology/Principal Findings: We identified organizations with five or more guidelines listed in the National Guideline Clearinghouse between January 1, 2009 and November 5, 2010. We obtained the COI policy for each organization from publicly accessible sources, most often the organization's website, and compared those polices to IOM standards related to COI. 37 organizations fulfilled our inclusion criteria, of which 17 (46%) had a COI policy directly related to CPGs. These COI policies varied widely with respect to types of COI addressed, from whom disclosures were collected, monetary thresholds for disclosure, approaches to management, and updating requirements. Not one organization's policy adhered to all seven of the IOM standards that were examined, and nine organizations did not meet a single one of the standards. Conclusions/Significance: COI policies among organizations producing a large number of CPGs currently do not measure up to IOM standards related to COI disclosure and management. CPG developers need to make significant improvements in these policies and their implementation in order to optimize the quality and credibility of their guidelines.

Suggested Citation

  • Susan L Norris & Haley K Holmer & Brittany U Burda & Lauren A Ogden & Rongwei Fu, 2012. "Conflict of Interest Policies for Organizations Producing a Large Number of Clinical Practice Guidelines," PLOS ONE, Public Library of Science, vol. 7(5), pages 1-12, May.
    • Handle: RePEc:plo:pone00:0037413
    DOI: 10.1371/journal.pone.0037413
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037413
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0037413&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0037413?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Rosie Taylor & Jim Giles, 2005. "Cash interests taint drug advice," Nature, Nature, vol. 437(7062), pages 1070-1071, October.
    2. Susan L Norris & Haley K Holmer & Lauren A Ogden & Brittany U Burda, 2011. "Conflict of Interest in Clinical Practice Guideline Development: A Systematic Review," PLOS ONE, Public Library of Science, vol. 6(10), pages 1-6, October.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Rachel Thompson & Zoe Paskins & Barry G. Main & Thaddeus Mason Pope & Evelyn C. Y. Chan & Ben W. Moulton & Michael J. Barry & Clarence H. Braddock III, 2021. "Addressing Conflicts of Interest in Health and Medicine: Current Evidence and Implications for Patient Decision Aid Development," Medical Decision Making, , vol. 41(7), pages 768-779, October.
    2. Tanya Graham & Phil Alderson & Tim Stokes, 2015. "Managing Conflicts of Interest in the UK National Institute for Health and Care Excellence (NICE) Clinical Guidelines Programme: Qualitative Study," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-10, March.
    3. Chase Meyer & Aaron Bowers & Cole Wayant & Jake Checketts & Jared Scott & Sanjeev Musuvathy & Matt Vassar, 2018. "Scientific evidence underlying the American College of Gastroenterology’s clinical practice guidelines," PLOS ONE, Public Library of Science, vol. 13(10), pages 1-9, October.
    4. Cristina Morciano & Vittorio Basevi & Carla Faralli & Michele Hilton Boon & Sabina Tonon & Domenica Taruscio, 2016. "Policies on Conflicts of Interest in Health Care Guideline Development: A Cross-Sectional Analysis," PLOS ONE, Public Library of Science, vol. 11(11), pages 1-24, November.
    5. Susan L Norris & Haley K Holmer & Lauren A Ogden & Shelley S Selph & Rongwei Fu, 2012. "Conflict of Interest Disclosures for Clinical Practice Guidelines in the National Guideline Clearinghouse," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-8, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Susan L Norris & Haley K Holmer & Lauren A Ogden & Brittany U Burda & Rongwei Fu, 2013. "Conflicts of Interest among Authors of Clinical Practice Guidelines for Glycemic Control in Type 2 Diabetes Mellitus," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-1, October.
    2. Susan L Norris & Haley K Holmer & Lauren A Ogden & Shelley S Selph & Rongwei Fu, 2012. "Conflict of Interest Disclosures for Clinical Practice Guidelines in the National Guideline Clearinghouse," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-8, November.
    3. Victoria S S Wong & Lauro Nathaniel Avalos & Michael L Callaham, 2019. "Industry payments to physician journal editors," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-11, February.
    4. Joanne Khabsa & Jennifer Petkovic & Alison Riddle & Lyubov Lytvyn & Olivia Magwood & Pearl Atwere & Pauline Campbell & Srinivasa V. Katikireddi & Bronwen Merner & Mona Nasser & Stephanie Chang & Aleja, 2022. "PROTOCOL: Conflict of interest issues when engaging stakeholders in health and healthcare guideline development: a systematic review," Campbell Systematic Reviews, John Wiley & Sons, vol. 18(2), June.
    5. Damien Wyssa & Martin R Tramèr & Nadia Elia, 2019. "Reporting of conflicts of interest and of sponsorship of guidelines in anaesthesiology. A cross-sectional study," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-13, February.
    6. Lisa Bero, 2018. "Meta-research matters: Meta-spin cycles, the blindness of bias, and rebuilding trust," PLOS Biology, Public Library of Science, vol. 16(4), pages 1-4, April.
    7. Joseph Pozsgai-Alvarez & Iván Pastor Sanz, 2021. "Mapping the (anti-)corruption field: key topics and changing trends, 1968–2020," Journal of Computational Social Science, Springer, vol. 4(2), pages 851-881, November.
    8. Unruh, Lynn & Rice, Thomas & Rosenau, Pauline Vaillancourt & Barnes, Andrew J., 2016. "The 2013 cholesterol guideline controversy: Would better evidence prevent pharmaceuticalization?," Health Policy, Elsevier, vol. 120(7), pages 797-808.
    9. Jeffrey Sonis & Olivia M Chen, 2020. "Approval processes in evidence-based clinical practice guidelines sponsored by medical specialty societies," PLOS ONE, Public Library of Science, vol. 15(2), pages 1-9, February.
    10. Zhuoqiong (Charlie) Chen & Tobias Gesche, 2016. "Persistent bias in advice-giving," ECON - Working Papers 228, Department of Economics - University of Zurich, revised Oct 2017.
    11. Tanya Graham & Phil Alderson & Tim Stokes, 2015. "Managing Conflicts of Interest in the UK National Institute for Health and Care Excellence (NICE) Clinical Guidelines Programme: Qualitative Study," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-10, March.
    12. Susan L Norris & Haley K Holmer & Lauren A Ogden & Brittany U Burda, 2011. "Conflict of Interest in Clinical Practice Guideline Development: A Systematic Review," PLOS ONE, Public Library of Science, vol. 6(10), pages 1-6, October.
    13. Wang, Zhicheng & Bero, Lisa & Grundy, Quinn, 2021. "Understanding professional stakeholders’ active resistance to guideline implementation: The case of Canadian breast screening guidelines," Social Science & Medicine, Elsevier, vol. 269(C).
    14. Yidan Lu & Derek J Jones & Nour Sharara & Tonya Kaltenbach & Loren Laine & Kenneth McQuaid & Roy Soetikno & Venkataraman Subramanian & Alan Barkun, 2017. "Transparency ethics in practice: Revisiting financial conflicts of interest disclosure forms in clinical practice guidelines," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-11, August.
    15. Cristina Morciano & Vittorio Basevi & Carla Faralli & Michele Hilton Boon & Sabina Tonon & Domenica Taruscio, 2016. "Policies on Conflicts of Interest in Health Care Guideline Development: A Cross-Sectional Analysis," PLOS ONE, Public Library of Science, vol. 11(11), pages 1-24, November.
    16. Tao Liu & Benjamin Quasinowski & André Soares, 2020. "The Emulation and Adaptation of a Global Model of Clinical Practice Guidelines on Chronic Heart Failure in BRICS Countries: A Comparative Study," IJERPH, MDPI, vol. 17(5), pages 1-21, March.
    17. Sheryl Spithoff & Pamela Leece & Frank Sullivan & Nav Persaud & Peter Belesiotis & Liane Steiner, 2020. "Drivers of the opioid crisis: An appraisal of financial conflicts of interest in clinical practice guideline panels at the peak of opioid prescribing," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-15, January.
    18. John M McPartland, 2009. "Obesity, the Endocannabinoid System, and Bias Arising from Pharmaceutical Sponsorship," PLOS ONE, Public Library of Science, vol. 4(3), pages 1-7, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0037413. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.