IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0021286.html
   My bibliography  Save this article

Human Herpesvirus 8 Seropositivity Among Sexually Active Adults in Uganda

Author

Listed:
  • Fatma M Shebl
  • Sheila C Dollard
  • Ruth M Pfeiffer
  • Benon Biryahwaho
  • Minal M Amin
  • Stella S Munuo
  • Wolfgang Hladik
  • Ruth Parsons
  • Barry I Graubard
  • Sam M Mbulaiteye

Abstract

Introduction: Sexual transmission of human herpesvirus 8 (HHV8) has been implicated among homosexual men, but the evidence for sexual transmission among heterosexual individuals is controversial. We investigated the role of sexual transmission of HHV8 in a nationally representative sample in Uganda, where HHV8 infection is endemic and transmitted mostly during childhood. Materials and Methods: The study population was a subset of participants (n = 2681) from a population-based HIV/AIDS serobehavioral survey of adults aged 15–59 years conducted in 2004/2005. High risk for sexual transmission was assessed by questionnaire and serological testing for HIV and herpes simplex virus 2. Anti-HHV8 antibodies were measured using two enzyme immunoassays targeting synthetic peptides from the K8.1 and orf65 viral genes. The current study was restricted to 2288 sexually active adults. ORs and 95% CIs for HHV8 seropositivity were estimated by fitting logistic regression models with a random intercept using MPLUS and SAS software. Results: The weighted prevalence of HHV8 seropositivity was 56.2%, based on 1302 seropositive individuals, and it increased significantly with age (Ptrend

Suggested Citation

  • Fatma M Shebl & Sheila C Dollard & Ruth M Pfeiffer & Benon Biryahwaho & Minal M Amin & Stella S Munuo & Wolfgang Hladik & Ruth Parsons & Barry I Graubard & Sam M Mbulaiteye, 2011. "Human Herpesvirus 8 Seropositivity Among Sexually Active Adults in Uganda," PLOS ONE, Public Library of Science, vol. 6(6), pages 1-7, June.
    • Handle: RePEc:plo:pone00:0021286
    DOI: 10.1371/journal.pone.0021286
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021286
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0021286&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0021286?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. D. Pfeffermann & C. J. Skinner & D. J. Holmes & H. Goldstein & J. Rasbash, 1998. "Weighting for unequal selection probabilities in multilevel models," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 60(1), pages 23-40.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Hammon, Angelina & Zinn, Sabine, 2020. "Multiple imputation of binary multilevel missing not at random data," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 69(3), pages 547-564.
    2. Jungah Choi & Hyunsuk Han, 2023. "Understanding the Influence of Teacher-Student Relationship on Mathematics Achievement: Evidence From Korean Students," SAGE Open, , vol. 13(4), pages 21582440231, November.
    3. Woodward, Albert & Das, Abhik & Raskin, Ira E. & Morgan-Lopez, Antonio A., 2006. "An exploratory analysis of treatment completion and client and organizational factors using hierarchical linear modeling," Evaluation and Program Planning, Elsevier, vol. 29(4), pages 335-351, November.
    4. Woojin Chung & Roeul Kim, 2020. "A Reversal of the Association between Education Level and Obesity Risk during Ageing: A Gender-Specific Longitudinal Study in South Korea," IJERPH, MDPI, vol. 17(18), pages 1-19, September.
    5. Carrington C. J. Shepherd & Holly D. Clifford & Francis Mitrou & Shannon M. Melody & Ellen J. Bennett & Fay H. Johnston & Luke D. Knibbs & Gavin Pereira & Janessa L. Pickering & Teck H. Teo & Lea-Ann , 2019. "The Contribution of Geogenic Particulate Matter to Lung Disease in Indigenous Children," IJERPH, MDPI, vol. 16(15), pages 1-12, July.
    6. Patricia Dörr & Jan Pablo Burgard, 2019. "Data-driven transformations and survey-weighting for linear mixed models," Research Papers in Economics 2019-16, University of Trier, Department of Economics.
    7. Shepherd, Carrington CJ & Li, Jianghong & Mitrou, Francis & Zubrick, Stephen R., 2012. "Socioeconomic disparities in the mental health of Indigenous children in Western Australia," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 12, pages 1-1.
    8. Jorge Walter & Daniel Z. Levin & J. Keith Murnighan, 2015. "Reconnection Choices: Selecting the Most Valuable (vs. Most Preferred) Dormant Ties," Organization Science, INFORMS, vol. 26(5), pages 1447-1465, October.
    9. Borgini, Riccardo & Bianco, Paola Del & Salvati, Nicola & Schmid, Timo & Tzavidis, Nikos, 2015. "Modelling the distribution of health related quality of life of advanced melanoma patients in a longitudinal multi-centre clinical trial using M-quantile random effects regression," Discussion Papers 2015/19, Free University Berlin, School of Business & Economics.
    10. Mary Ying-Fang Wang & Paul Tuss & Lihong Qi, 2019. "Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model," Psychometrika, Springer;The Psychometric Society, vol. 84(2), pages 447-467, June.
    11. Jennings, Jacky M. & Hensel, Devon J. & Tanner, Amanda E. & Reilly, Meredith L. & Ellen, Jonathan M., 2014. "Are social organizational factors independently associated with a current bacterial sexually transmitted infection among urban adolescents and young adults?," Social Science & Medicine, Elsevier, vol. 118(C), pages 52-60.
    12. Joseph L Dieleman & Tara Templin, 2014. "Random-Effects, Fixed-Effects and the within-between Specification for Clustered Data in Observational Health Studies: A Simulation Study," PLOS ONE, Public Library of Science, vol. 9(10), pages 1-17, October.
    13. Woojin Chung & Roeul Kim, 2020. "Differential Risk of Cognitive Impairment across Paid and Unpaid Occupations in the Middle-Age Population: Evidence from the Korean Longitudinal Study of Aging, 2006–2016," IJERPH, MDPI, vol. 17(9), pages 1-14, April.
    14. Laura M. Stapleton & Yoonjeong Kang, 2018. "Design Effects of Multilevel Estimates From National Probability Samples," Sociological Methods & Research, , vol. 47(3), pages 430-457, August.
    15. Deping Li & Andreas Oranje & Yanlin Jiang, 2009. "On the Estimation of Hierarchical Latent Regression Models for Large-Scale Assessments," Journal of Educational and Behavioral Statistics, , vol. 34(4), pages 433-463, December.
    16. Woojin Chung & Roeul Kim, 2020. "Which Occupation is Highly Associated with Cognitive Impairment? A Gender-Specific Longitudinal Study of Paid and Unpaid Occupations in South Korea," IJERPH, MDPI, vol. 17(21), pages 1-17, October.
    17. Nora Würz & Timo Schmid & Nikos Tzavidis, 2022. "Estimating regional income indicators under transformations and access to limited population auxiliary information," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 185(4), pages 1679-1706, October.
    18. West Brady T. & Sakshaug Joseph W. & Aurelien Guy Alain S., 2018. "Accounting for Complex Sampling in Survey Estimation: A Review of Current Software Tools," Journal of Official Statistics, Sciendo, vol. 34(3), pages 721-752, September.
    19. Simone Santoni & Paolo Ferri & Maria Lusiani, 2013. "Novelty Conduits and Forms of Network Ties: To Bond or to Bridge?," Working Papers 34, Venice School of Management - Department of Management, Università Ca' Foscari Venezia.
    20. Bunger, Alicia C. & Chuang, Emmeline & McBeath, Bowen, 2012. "Facilitating mental health service use for caregivers: Referral strategies among child welfare caseworkers," Children and Youth Services Review, Elsevier, vol. 34(4), pages 696-703.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0021286. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.