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On-line Randomized Controlled Trial of an Internet Based Psychologically Enhanced Intervention for People with Hazardous Alcohol Consumption

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Listed:
  • Paul Wallace
  • Elizabeth Murray
  • Jim McCambridge
  • Zarnie Khadjesari
  • Ian R White
  • Simon G Thompson
  • Eleftheria Kalaitzaki
  • Christine Godfrey
  • Stuart Linke

Abstract

Background: Interventions delivered via the Internet have the potential to address the problem of hazardous alcohol consumption at minimal incremental cost, with potentially major public health implications. It was hypothesised that providing access to a psychologically enhanced website would result in greater reductions in drinking and related problems than giving access to a typical alcohol website simply providing information on potential harms of alcohol. DYD-RCT Trial registration: ISRCTN 31070347. Methodology/Principal Findings: A two-arm randomised controlled trial was conducted entirely on-line through the Down Your Drink (DYD) website. A total of 7935 individuals who screened positive for hazardous alcohol consumption were recruited and randomized. At entry to the trial, the geometric mean reported past week alcohol consumption was 46.0 (SD 31.2) units. Consumption levels reduced substantially in both groups at the principal 3 month assessment point to an average of 26.0 (SD 22.3) units. Similar changes were reported at 1 month and 12 months. There were no significant differences between the groups for either alcohol consumption at 3 months (intervention: control ratio of geometric means 1.03, 95% CI 0.97 to 1.10) or for this outcome and the main secondary outcomes at any of the assessments. The results were not materially changed following imputation of missing values, nor was there any evidence that the impact of the intervention varied with baseline measures or level of exposure to the intervention. Conclusions/Significance: Findings did not provide support for the hypothesis that access to a psychologically enhanced website confers additional benefit over standard practice and indicate the need for further research to optimise the effectiveness of Internet-based behavioural interventions. The trial demonstrates a widespread and potentially sustainable demand for Internet based interventions for people with hazardous alcohol consumption, which could be delivered internationally. Trial Registration: Controlled-Trials.com ISRCTN31070347

Suggested Citation

  • Paul Wallace & Elizabeth Murray & Jim McCambridge & Zarnie Khadjesari & Ian R White & Simon G Thompson & Eleftheria Kalaitzaki & Christine Godfrey & Stuart Linke, 2011. "On-line Randomized Controlled Trial of an Internet Based Psychologically Enhanced Intervention for People with Hazardous Alcohol Consumption," PLOS ONE, Public Library of Science, vol. 6(3), pages 1-8, March.
    • Handle: RePEc:plo:pone00:0014740
    DOI: 10.1371/journal.pone.0014740
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    References listed on IDEAS

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    1. Paul Kind & Geoffrey Hardman & Susan Macran, 1999. "UK population norms for EQ-5D," Working Papers 172chedp, Centre for Health Economics, University of York.
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    1. Heleen Riper & Matthijs Blankers & Hana Hadiwijaya & John Cunningham & Stella Clarke & Reinout Wiers & David Ebert & Pim Cuijpers, 2014. "Effectiveness of Guided and Unguided Low-Intensity Internet Interventions for Adult Alcohol Misuse: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-11, June.
    2. Zarnie Khadjesari & Dorothy Newbury-Birch & Elizabeth Murray & Don Shenker & Louise Marston & Eileen Kaner, 2015. "Online Health Check for Reducing Alcohol Intake among Employees: A Feasibility Study in Six Workplaces across England," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-18, March.
    3. Zarnie Khadjesari & Nick Freemantle & Stuart Linke & Rachael Hunter & Elizabeth Murray, 2014. "Health on the Web: Randomised Controlled Trial of Online Screening and Brief Alcohol Intervention Delivered in a Workplace Setting," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-9, November.
    4. Christopher Sundström & Mikael Gajecki & Magnus Johansson & Matthijs Blankers & Kristina Sinadinovic & Erik Stenlund-Gens & Anne H Berman, 2016. "Guided and Unguided Internet-Based Treatment for Problematic Alcohol Use – A Randomized Controlled Pilot Trial," PLOS ONE, Public Library of Science, vol. 11(7), pages 1-19, July.

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