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Cost-effectiveness evidence of mental health prevention and promotion interventions: A systematic review of economic evaluations

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  • Long Khanh-Dao Le
  • Adrian Cuevas Esturas
  • Cathrine Mihalopoulos
  • Oxana Chiotelis
  • Jessica Bucholc
  • Mary Lou Chatterton
  • Lidia Engel

Abstract

Background: The prevention of mental disorders and promotion of mental health and well-being are growing fields. Whether mental health promotion and prevention interventions provide value for money in children, adolescents, adults, and older adults is unclear. The aim of the current study is to update 2 existing reviews of cost-effectiveness studies in this field in order to determine whether such interventions are cost-effective. Methods and findings: Electronic databases (including MEDLINE, PsycINFO, CINAHL, and EconLit through EBSCO and Embase) were searched for published cost-effectiveness studies of prevention of mental disorders and promotion of mental health and well-being from 2008 to 2020. The quality of studies was assessed using the Quality of Health Economic Studies Instrument (QHES). The protocol was registered with PROSPERO (# CRD42019127778). The primary outcomes were incremental cost-effectiveness ratio (ICER) or return on investment (ROI) ratio across all studies. Conclusions: Our review found a significant growth of economic evaluations in prevention of mental disorders or promotion of mental health and well-being over the last 10 years. Although several interventions for mental health prevention and promotion provide good value for money, the varied quality as well as methodologies used in economic evaluations limit the generalisability of conclusions about cost-effectiveness. However, the finding that the majority of studies especially in children, adolescents, and adults demonstrated good value for money is promising. Research on cost-effectiveness in low-middle income settings is required. Trial registration: PROSPERO registration number: CRD42019127778. In a systematic review, Long Khanh-Dao Le and colleagues investigate the cost effectiveness of mental health interventions among children, adolescents, and adults.Why was this study done?: What did the researchers do and find?: What do these findings mean?:

Suggested Citation

  • Long Khanh-Dao Le & Adrian Cuevas Esturas & Cathrine Mihalopoulos & Oxana Chiotelis & Jessica Bucholc & Mary Lou Chatterton & Lidia Engel, 2021. "Cost-effectiveness evidence of mental health prevention and promotion interventions: A systematic review of economic evaluations," PLOS Medicine, Public Library of Science, vol. 18(5), pages 1-27, May.
    • Handle: RePEc:plo:pmed00:1003606
    DOI: 10.1371/journal.pmed.1003606
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    Cited by:

    1. Nina Ponikvar & Marija Anderluh & Eva Strmljan Kreslin & Mojca Marc, 2021. "Economic Evaluation of Preventive Healthcare: A Cost Benefit Analysis of a Parenting Program," Eurasian Journal of Social Sciences, Eurasian Publications, vol. 9(2), pages 89-97.
    2. Rachael Taylor & Deborah Sullivan & Penny Reeves & Nicola Kerr & Amy Sawyer & Emma Schwartzkoff & Andrew Bailey & Christopher Williams & Alexis Hure, 2023. "A Scoping Review of Economic Evaluations to Inform the Reorientation of Preventive Health Services in Australia," IJERPH, MDPI, vol. 20(12), pages 1-47, June.

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