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The evolution and performance of biotechnology regional systems of innovation

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  • Jorge Niosi
  • Marc Banik

Abstract

The paper maintains that biotechnology regions develop as complex systems: they start with star scientists in research universities, generating knowledge spillovers, then move progressively towards regional technology markets. In the process they attract venture capital (or modify the behaviour of existing venture capital firms with the addition of biotechnology portfolios). The routines of universities are also modified with the addition of intellectual property and technology transfer offices intervening as sellers in the newly created knowledge markets. The paper also considers whether companies located in regional agglomerations grow faster than isolated ones, and whether companies spun-off from universities have a better performance than start-ups. The study is based on about 90 Canadian-based publicly quoted biotechnology companies. Copyright 2005, Oxford University Press.

Suggested Citation

  • Jorge Niosi & Marc Banik, 2005. "The evolution and performance of biotechnology regional systems of innovation," Cambridge Journal of Economics, Cambridge Political Economy Society, vol. 29(3), pages 343-357, May.
    • Handle: RePEc:oup:cambje:v:29:y:2005:i:3:p:343-357
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    File URL: http://hdl.handle.net/10.1093/cje/bei044
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    Cited by:

    1. Li, Yingbo & Wei, Yigang & Li, Yan & Lei, Zhen & Ceriani, Alessandra, 2022. "Connecting emerging industry and regional innovation system: Linkages, effect and paradigm in China," Technovation, Elsevier, vol. 111(C).
    2. Martine Gadille & Juan Ramón Gallego-Bono, 2021. "Rebuilding a Cluster While Protecting Knowledge within Low-Medium-Tech Supplier SMEs: A Spanish and French Comparison," Sustainability, MDPI, vol. 13(20), pages 1-35, October.
    3. Broekel, Tom & Fornahl, Dirk & Morrison, Andrea, 2015. "Another cluster premium: Innovation subsidies and R&D collaboration networks," Research Policy, Elsevier, vol. 44(8), pages 1431-1444.
    4. Dorsa Tajaddod Alizadeh & Andrea Schiffauerova, 2018. "Evaluation Of Effects Of Collaborative Patterns On The Efficiency Of Scientific Networks Using Simulation," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 22(04), pages 1-28, May.
    5. Marco Capasso & Elena Cefis & Koen Frenken, 2009. "Do Some Firms Persistently Outperform ?," LEM Papers Series 2009/15, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
    6. Kshetri, Nir & Dholakia, Nikhilesh, 2009. "Professional and trade associations in a nascent and formative sector of a developing economy: A case study of the NASSCOM effect on the Indian offshoring industry," Journal of International Management, Elsevier, vol. 15(2), pages 225-239, June.
    7. Alessandro Rosiello & Stuart Parris, 2009. "The patterns of venture capital investment in the UK bio-healthcare sector: the role of proximity, cumulative learning and specialisation," Venture Capital, Taylor & Francis Journals, vol. 11(3), pages 185-211, February.
    8. Der-Shiuan Lee, 2018. "Towards Urban Resilience through Inter-City Networks of Co-Invention: A Case Study of U.S. Cities," Sustainability, MDPI, vol. 10(2), pages 1-23, January.
    9. Papaioannou, Theo & Watkins, Andrew & Mugwagwa, Julius & Kale, Dinar, 2016. "To Lobby or to Partner? Investigating the Shifting Political Strategies of Biopharmaceutical Industry Associations in Innovation Systems of South Africa and India," World Development, Elsevier, vol. 78(C), pages 66-79.
    10. Su, Yu-Shan & Wu, Feng-Shang, 2015. "Regional systems of biotechnology innovation — The case of Taiwan," Technological Forecasting and Social Change, Elsevier, vol. 100(C), pages 96-106.
    11. Breandán hUallacháin & Der-Shiuan Lee, 2014. "Urban centers and networks of co-invention in American biotechnology," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 52(3), pages 799-823, May.
    12. María Eugenia Castelao Caruana & Mariel de Vita & Pablo Lavarello, 2021. "Proximidades en el aprendizaje tecnológico: aportes metodológicos para el estudio de los entramados locales en América Latina," Ensayos de Economía 20138, Universidad Nacional de Colombia Sede Medellín.
    13. Tom Broekel & Holger Graf, 2010. "Structural properties of cooperation networks in Germany: From basic to applied research," Jena Economics Research Papers 2010-078, Friedrich-Schiller-University Jena.
    14. Jorge Niosi, 2010. "Building National and Regional Innovation Systems," Books, Edward Elgar Publishing, number 14006.
    15. Hurmelinna-Laukkanen, Pia & Möller, Kristian & Nätti, Satu, 2022. "Orchestrating innovation networks: Alignment and orchestration profile approach," Journal of Business Research, Elsevier, vol. 140(C), pages 170-188.
    16. Christoph Roesler & Tom Broekel, 2017. "The role of universities in a network of subsidized R&D collaboration: The case of the biotechnology-industry in Germany," Review of Regional Research: Jahrbuch für Regionalwissenschaft, Springer;Gesellschaft für Regionalforschung (GfR), vol. 37(2), pages 135-160, October.

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