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How the amino acid leucine activates the key cell-growth regulator mTOR

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  • Tibor Vellai

Abstract

Cells can tailor their growth to current conditions by sensing nutrients. The protein complex mTORC1 enables cell growth to be coordinated with the level of certain amino acids, and how it senses the amino acid leucine has now become clearer.

Suggested Citation

  • Tibor Vellai, 2021. "How the amino acid leucine activates the key cell-growth regulator mTOR," Nature, Nature, vol. 596(7871), pages 192-194, August.
    • Handle: RePEc:nat:nature:v:596:y:2021:i:7871:d:10.1038_d41586-021-01943-7
    DOI: 10.1038/d41586-021-01943-7
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    Cited by:

    1. Ádám Sturm & Éva Saskői & Bernadette Hotzi & Anna Tarnóci & János Barna & Ferenc Bodnár & Himani Sharma & Tibor Kovács & Eszter Ari & Nóra Weinhardt & Csaba Kerepesi & András Perczel & Zoltán Ivics & , 2023. "Downregulation of transposable elements extends lifespan in Caenorhabditis elegans," Nature Communications, Nature, vol. 14(1), pages 1-18, December.

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    Keywords

    Cell biology; Metabolism; Cancer;
    All these keywords.

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