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High performance plasma amyloid-β biomarkers for Alzheimer’s disease

Author

Listed:
  • Akinori Nakamura

    (Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology)

  • Naoki Kaneko

    (Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation)

  • Victor L. Villemagne

    (Austin Health, Center for PET, Heidelberg
    The Florey Institute, The University of Melbourne)

  • Takashi Kato

    (Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology
    National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology)

  • James Doecke

    (Health and Biosecurity, CSIRO)

  • Vincent Doré

    (Austin Health, Center for PET, Heidelberg
    Health and Biosecurity, CSIRO)

  • Chris Fowler

    (The Florey Institute, The University of Melbourne)

  • Qiao-Xin Li

    (The Florey Institute, The University of Melbourne)

  • Ralph Martins

    (Edith Cowan University)

  • Christopher Rowe

    (Austin Health, Center for PET, Heidelberg
    The Florey Institute, The University of Melbourne)

  • Taisuke Tomita

    (Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

  • Katsumi Matsuzaki

    (Graduate School of Pharmaceutical Sciences, Kyoto University)

  • Kenji Ishii

    (Team for Neuroimaging Research, Tokyo Metropolitan Institute of Gerontology)

  • Kazunari Ishii

    (Kindai University Faculty of Medicine, Osakasayama)

  • Yutaka Arahata

    (National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology)

  • Shinichi Iwamoto

    (Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation)

  • Kengo Ito

    (Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology
    National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology)

  • Koichi Tanaka

    (Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation)

  • Colin L. Masters

    (The Florey Institute, The University of Melbourne)

  • Katsuhiko Yanagisawa

    (Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology)

Abstract

Measurement of human plasma amyloid-β biomarkers using immunoprecipitation coupled with mass spectrometry reliably predicts individual brain amyloid-β status and has potential clinical utility.

Suggested Citation

  • Akinori Nakamura & Naoki Kaneko & Victor L. Villemagne & Takashi Kato & James Doecke & Vincent Doré & Chris Fowler & Qiao-Xin Li & Ralph Martins & Christopher Rowe & Taisuke Tomita & Katsumi Matsuzaki, 2018. "High performance plasma amyloid-β biomarkers for Alzheimer’s disease," Nature, Nature, vol. 554(7691), pages 249-254, February.
    • Handle: RePEc:nat:nature:v:554:y:2018:i:7691:d:10.1038_nature25456
    DOI: 10.1038/nature25456
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    Cited by:

    1. Kazumasa Yamada & Kenta Murotani & Makiko Mano & Youngmi Lim & Jun Yoshimatsu, 2023. "Age-Friendly Approach Is Necessary to Prevent Depopulation: Resident Architectural Designers and Constructors’ Evaluation of the Age-Friendliness of Japanese Municipalities," IJERPH, MDPI, vol. 20(17), pages 1-11, August.
    2. Lijun Zhou & Sihui Wu & Yunyi Chen & Runhuan Huang & Bixuan Cheng & Qingyi Mao & Tinghan Liu & Yuchen Liu & Kai Zhao & Huitang Pan & Chao Yu & Xiang Gao & Le Luo & Qixiang Zhang, 2024. "Multi-omics analyzes of Rosa gigantea illuminate tea scent biosynthesis and release mechanisms," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    3. Xin Huang & Chris Fowler & Yihan Li & Qiao-Xin Li & Jiaqi Sun & Yijun Pan & Liang Jin & Keyla A. Perez & Céline Dubois & Yen Y. Lim & Candace Drysdale & Rebecca L. Rumble & Holly R. Chinnery & Christo, 2024. "Clearance and transport of amyloid β by peripheral monocytes correlate with Alzheimer’s disease progression," Nature Communications, Nature, vol. 15(1), pages 1-17, December.

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