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Biotechnological mass production of DNA origami

Author

Listed:
  • Florian Praetorius

    (Technical University of Munich)

  • Benjamin Kick

    (Technical University of Munich
    Technical University of Munich, Institute of Biochemical Engineering)

  • Karl L. Behler

    (Technical University of Munich, Institute of Biochemical Engineering)

  • Maximilian N. Honemann

    (Technical University of Munich)

  • Dirk Weuster-Botz

    (Technical University of Munich, Institute of Biochemical Engineering)

  • Hendrik Dietz

    (Technical University of Munich)

Abstract

All necessary strands for DNA origami can be created in a single scalable process by using bacteriophages to generate single-stranded precursor DNA containing the target sequences interleaved with self-excising DNA enzymes.

Suggested Citation

  • Florian Praetorius & Benjamin Kick & Karl L. Behler & Maximilian N. Honemann & Dirk Weuster-Botz & Hendrik Dietz, 2017. "Biotechnological mass production of DNA origami," Nature, Nature, vol. 552(7683), pages 84-87, December.
    • Handle: RePEc:nat:nature:v:552:y:2017:i:7683:d:10.1038_nature24650
    DOI: 10.1038/nature24650
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    Citations

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    Cited by:

    1. Yahong Chen & Chaoyong Yang & Zhi Zhu & Wei Sun, 2022. "Suppressing high-dimensional crystallographic defects for ultra-scaled DNA arrays," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    2. Shekaari, Ashkan & Jafari, Mahmoud, 2019. "Statistical mechanical modeling of a DNA nanobiostructure at the base-pair level," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 518(C), pages 80-88.
    3. Mária Brunderová & Vojtěch Havlíček & Ján Matyašovský & Radek Pohl & Lenka Poštová Slavětínská & Matouš Krömer & Michal Hocek, 2024. "Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    4. Jessica A. Kretzmann & Anna Liedl & Alba Monferrer & Volodymyr Mykhailiuk & Samuel Beerkens & Hendrik Dietz, 2023. "Gene-encoding DNA origami for mammalian cell expression," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    5. Ruohong Shi & Kuan-Lin Chen & Joshua Fern & Siming Deng & Yixin Liu & Dominic Scalise & Qi Huang & Noah J. Cowan & David H. Gracias & Rebecca Schulman, 2024. "Programming gel automata shapes using DNA instructions," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

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