IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v548y2017i7669d10.1038_nature23663.html
   My bibliography  Save this article

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

Author

Listed:
  • Kai Liu

    (Johns Hopkins University School of Medicine)

  • Juhyun Kim

    (Johns Hopkins University School of Medicine)

  • Dong Won Kim

    (Johns Hopkins University School of Medicine)

  • Yi Stephanie Zhang

    (Johns Hopkins University School of Medicine)

  • Hechen Bao

    (University of North Carolina School of Medicine)

  • Myrto Denaxa

    (The Francis Crick Institute)

  • Szu-Aun Lim

    (University of North Carolina School of Medicine)

  • Eileen Kim

    (Johns Hopkins University)

  • Chang Liu

    (Johns Hopkins University School of Medicine)

  • Ian R. Wickersham

    (The McGovern Institute for Brain Research, Massachusetts Institute of Technology)

  • Vassilis Pachnis

    (The Francis Crick Institute)

  • Samer Hattar

    (National Institute of Mental Health)

  • Juan Song

    (University of North Carolina School of Medicine)

  • Solange P. Brown

    (Johns Hopkins University School of Medicine)

  • Seth Blackshaw

    (Johns Hopkins University School of Medicine)

Abstract

GABAergic Lhx6+ neurons in the ventral zona incerta promote both rapid eye movement and non-rapid eye movement sleep and inhibit the activity of wake-promoting GABAergic and Hcrt+ neurons of the lateral hypothalamus.

Suggested Citation

  • Kai Liu & Juhyun Kim & Dong Won Kim & Yi Stephanie Zhang & Hechen Bao & Myrto Denaxa & Szu-Aun Lim & Eileen Kim & Chang Liu & Ian R. Wickersham & Vassilis Pachnis & Samer Hattar & Juan Song & Solange , 2017. "Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep," Nature, Nature, vol. 548(7669), pages 582-587, August.
  • Handle: RePEc:nat:nature:v:548:y:2017:i:7669:d:10.1038_nature23663
    DOI: 10.1038/nature23663
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature23663
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature23663?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Han Guo & Jian-Bo Jiang & Wei Xu & Mu-Tian Zhang & Hui Chen & Huan-Ying Shi & Lu Wang & Miao He & Michael Lazarus & Shan-Qun Li & Zhi-Li Huang & Wei-Min Qu, 2023. "Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    2. Jilin W J L Wang & Fabrizio Lombardi & Xiyun Zhang & Christelle Anaclet & Plamen Ch Ivanov, 2019. "Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture," PLOS Computational Biology, Public Library of Science, vol. 15(11), pages 1-35, November.
    3. Fernando M. C. V. Reis & Sandra Maesta-Pereira & Matthias Ollivier & Peter J. Schuette & Ekayana Sethi & Blake A. Miranda & Emily Iniguez & Meghmik Chakerian & Eric Vaughn & Megha Sehgal & Darren C. T, 2024. "Control of feeding by a bottom-up midbrain-subthalamic pathway," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    4. Sasa Teng & Fenghua Zhen & Li Wang & Jose Canovas Schalchli & Jane Simko & Xinyue Chen & Hao Jin & Christopher D. Makinson & Yueqing Peng, 2022. "Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area," Nature Communications, Nature, vol. 13(1), pages 1-15, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:548:y:2017:i:7669:d:10.1038_nature23663. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.