IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v547y2017i7664d10.1038_nature23284.html
   My bibliography  Save this article

Cysteine protease cathepsin B mediates radiation-induced bystander effects

Author

Listed:
  • Yu Peng

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University)

  • Man Zhang

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University)

  • Lingjun Zheng

    (Cellular, and Developmental Biology, University of Colorado
    College of Food Science, Fujian Agriculture and Forestry University)

  • Qian Liang

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University)

  • Hanzeng Li

    (Cellular, and Developmental Biology, University of Colorado)

  • Jeng-Ting Chen

    (Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University and Liver Research Center, Chang Gung Memorial Hospital at Linkou)

  • Hongyan Guo

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University)

  • Sawako Yoshina

    (Tokyo Women’s Medical University School of Medicine and Core Research for Embryonic Science and Technology (CREST), Japan Science and Technology Agency (JST))

  • Yu-Zen Chen

    (Cellular, and Developmental Biology, University of Colorado)

  • Xiang Zhao

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University)

  • Xiaoqi Wu

    (Cellular, and Developmental Biology, University of Colorado
    College of Food Science, Fujian Agriculture and Forestry University)

  • Bin Liu

    (College of Food Science, Fujian Agriculture and Forestry University)

  • Shohei Mitani

    (Tokyo Women’s Medical University School of Medicine and Core Research for Embryonic Science and Technology (CREST), Japan Science and Technology Agency (JST))

  • Jau-Song Yu

    (Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University and Liver Research Center, Chang Gung Memorial Hospital at Linkou)

  • Ding Xue

    (School of Life Sciences & Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University
    Cellular, and Developmental Biology, University of Colorado)

Abstract

The cysteine protease CPR-4, a cathepsin B homologue, is identified as a radiation-induced bystander effect (RIBE) factor in nematodes in response to ultraviolet or ionizing radiation, and causes inhibition of cell death and increased embryonic lethality.

Suggested Citation

  • Yu Peng & Man Zhang & Lingjun Zheng & Qian Liang & Hanzeng Li & Jeng-Ting Chen & Hongyan Guo & Sawako Yoshina & Yu-Zen Chen & Xiang Zhao & Xiaoqi Wu & Bin Liu & Shohei Mitani & Jau-Song Yu & Ding Xue, 2017. "Cysteine protease cathepsin B mediates radiation-induced bystander effects," Nature, Nature, vol. 547(7664), pages 458-462, July.
    • Handle: RePEc:nat:nature:v:547:y:2017:i:7664:d:10.1038_nature23284
    DOI: 10.1038/nature23284
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature23284
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature23284?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Shi-ming Li & Dan Liu & Yi-lin Liu & Bin Liu & Xing-huang Chen, 2020. "Quercetin and Its Mixture Increase the Stress Resistance of Caenorhabditis elegans to UV-B," IJERPH, MDPI, vol. 17(5), pages 1-13, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:547:y:2017:i:7664:d:10.1038_nature23284. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.