IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v547y2017i7661d10.1038_nature22993.html
   My bibliography  Save this article

Tracing the origins of relapse in acute myeloid leukaemia to stem cells

Author

Listed:
  • Liran I. Shlush

    (Princess Margaret Cancer Centre, University Health Network
    Weizmann Institute of Science
    Division of Hematology Rambam Healthcare Campus)

  • Amanda Mitchell

    (Princess Margaret Cancer Centre, University Health Network)

  • Lawrence Heisler

    (Ontario Institute for Cancer Research)

  • Sagi Abelson

    (Princess Margaret Cancer Centre, University Health Network)

  • Stanley W. K. Ng

    (Princess Margaret Cancer Centre, University Health Network)

  • Aaron Trotman-Grant

    (Princess Margaret Cancer Centre, University Health Network)

  • Jessie J. F. Medeiros

    (Princess Margaret Cancer Centre, University Health Network)

  • Abilasha Rao-Bhatia

    (Princess Margaret Cancer Centre, University Health Network)

  • Ivana Jaciw-Zurakowsky

    (Princess Margaret Cancer Centre, University Health Network)

  • Rene Marke

    (Laboratory of Pediatric Oncology, Radboud University Medical Center)

  • Jessica L. McLeod

    (Princess Margaret Cancer Centre, University Health Network)

  • Monica Doedens

    (Princess Margaret Cancer Centre, University Health Network)

  • Gary Bader

    (University of Toronto
    Donnelly Centre for Cellular and Biomolecular Research)

  • Veronique Voisin

    (Donnelly Centre for Cellular and Biomolecular Research)

  • ChangJiang Xu

    (Donnelly Centre for Cellular and Biomolecular Research)

  • John D. McPherson

    (Ontario Institute for Cancer Research)

  • Thomas J. Hudson

    (Ontario Institute for Cancer Research
    University of Toronto
    University of Toronto)

  • Jean C. Y. Wang

    (Princess Margaret Cancer Centre, University Health Network
    University of Toronto
    University Health Network)

  • Mark D. Minden

    (Princess Margaret Cancer Centre, University Health Network
    University of Toronto
    University of Toronto
    University Health Network)

  • John E. Dick

    (Princess Margaret Cancer Centre, University Health Network
    University of Toronto)

Abstract

Identification of the cell types from which relapse arises in acute myeloid leukaemia, by following leukaemia propagation from patient-derived leukaemia samples.

Suggested Citation

  • Liran I. Shlush & Amanda Mitchell & Lawrence Heisler & Sagi Abelson & Stanley W. K. Ng & Aaron Trotman-Grant & Jessie J. F. Medeiros & Abilasha Rao-Bhatia & Ivana Jaciw-Zurakowsky & Rene Marke & Jessi, 2017. "Tracing the origins of relapse in acute myeloid leukaemia to stem cells," Nature, Nature, vol. 547(7661), pages 104-108, July.
    • Handle: RePEc:nat:nature:v:547:y:2017:i:7661:d:10.1038_nature22993
    DOI: 10.1038/nature22993
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature22993
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature22993?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Jenny Karlsson & Hiroaki Yasui & Adriana Mañas & Natalie Andersson & Karin Hansson & Kristina Aaltonen & Caroline Jansson & Geoffroy Durand & Naveen Ravi & Michele Ferro & Minjun Yang & Subhayan Chatt, 2024. "Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    2. Matteo Maria Naldini & Gabriele Casirati & Matteo Barcella & Paola Maria Vittoria Rancoita & Andrea Cosentino & Carolina Caserta & Francesca Pavesi & Erika Zonari & Giacomo Desantis & Diego Gilioli & , 2023. "Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
    3. Naomi Kawashima & Yuichi Ishikawa & Jeong Hui Kim & Yoko Ushijima & Akimi Akashi & Yohei Yamaguchi & Hikaru Hattori & Marie Nakashima & Seara Ikeno & Rika Kihara & Takahiro Nishiyama & Takanobu Morish, 2022. "Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    4. N. Zioni & A. Akhiad Bercovich & N. Chapal-Ilani & Tal Bacharach & N. Rappoport & A. Solomon & R. Avraham & E. Kopitman & Z. Porat & M. Sacma & G. Hartmut & M. Scheller & C. Muller-Tidow & D. Lipka & , 2023. "Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:547:y:2017:i:7661:d:10.1038_nature22993. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.