IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v545y2017i7655d10.1038_nature22350.html
   My bibliography  Save this article

Identification of preoptic sleep neurons using retrograde labelling and gene profiling

Author

Listed:
  • Shinjae Chung

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Franz Weber

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Peng Zhong

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Chan Lek Tan

    (University of California, San Francisco)

  • Thuc Nghi Nguyen

    (Allen Institute for Brain Science)

  • Kevin T. Beier

    (Howard Hughes Medical Institute, Stanford University)

  • Nikolai Hörmann

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Wei-Cheng Chang

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Zhe Zhang

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Johnny Phong Do

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

  • Shenqin Yao

    (Allen Institute for Brain Science)

  • Michael J. Krashes

    (Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
    National Institute on Drug Abuse, National Institutes of Health)

  • Bosiljka Tasic

    (Allen Institute for Brain Science)

  • Ali Cetin

    (Allen Institute for Brain Science)

  • Hongkui Zeng

    (Allen Institute for Brain Science)

  • Zachary A. Knight

    (University of California, San Francisco)

  • Liqun Luo

    (Howard Hughes Medical Institute, Stanford University)

  • Yang Dan

    (Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California)

Abstract

Identification of sleep-active and sleep-promoting neurons in the preoptic area of the hypothalamus using neural projection tracing tools to target this population among a group of intermingled neurons, all with various functions.

Suggested Citation

  • Shinjae Chung & Franz Weber & Peng Zhong & Chan Lek Tan & Thuc Nghi Nguyen & Kevin T. Beier & Nikolai Hörmann & Wei-Cheng Chang & Zhe Zhang & Johnny Phong Do & Shenqin Yao & Michael J. Krashes & Bosil, 2017. "Identification of preoptic sleep neurons using retrograde labelling and gene profiling," Nature, Nature, vol. 545(7655), pages 477-481, May.
  • Handle: RePEc:nat:nature:v:545:y:2017:i:7655:d:10.1038_nature22350
    DOI: 10.1038/nature22350
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature22350
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature22350?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ruina Wang & Lei Xiao & Jianbo Pan & Guangsen Bao & Yunmei Zhu & Di Zhu & Jun Wang & Chengfeng Pei & Qinfeng Ma & Xian Fu & Ziruoyu Wang & Mengdi Zhu & Guoxiang Wang & Ling Gong & Qiuping Tong & Min J, 2023. "Natural product P57 induces hypothermia through targeting pyridoxal kinase," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Shuancheng Ren & Cai Zhang & Faguo Yue & Jinxiang Tang & Wei Zhang & Yue Zheng & Yuanyuan Fang & Na Wang & Zhenbo Song & Zehui Zhang & Xiaolong Zhang & Han Qin & Yaling Wang & Jianxia Xia & Chenggang , 2024. "A midbrain GABAergic circuit constrains wakefulness in a mouse model of stress," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    3. Sasa Teng & Fenghua Zhen & Li Wang & Jose Canovas Schalchli & Jane Simko & Xinyue Chen & Hao Jin & Christopher D. Makinson & Yueqing Peng, 2022. "Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    4. Roberto Luca & Stefano Nardone & Kevin P. Grace & Anne Venner & Michela Cristofolini & Sathyajit S. Bandaru & Lauren T. Sohn & Dong Kong & Takatoshi Mochizuki & Bianca Viberti & Lin Zhu & Antonino Zit, 2022. "Orexin neurons inhibit sleep to promote arousal," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    5. Can Tao & Guang-Wei Zhang & Wen-Jian Sun & Junxiang J. Huang & Li I. Zhang & Huizhong Whit Tao, 2024. "Excitation-inhibition imbalance in medial preoptic area circuits underlies chronic stress-induced depression-like states," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:545:y:2017:i:7655:d:10.1038_nature22350. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.